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Tmem69 Gene Detail
Summary
  • Symbol
    Tmem69
  • Name
    transmembrane protein 69
  • Synonyms
    A630048M13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045357
    NCBI Gene: 230657
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:116409102-116413132 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045357
 protein coding gene Chr4:116408725-116414262 (-)
129S1/SvImJ ENSMUSG00200048070
 protein coding gene Chr4:110304749-110311557 (-)
A/J ENSMUSG00195046319
 protein coding gene Chr4:111569559-111576367 (-)
AKR/J ENSMUSG00220010652
 protein coding gene Chr4:110912404-110919214 (-)
BALB/cJ ENSMUSG00180040193
 protein coding gene Chr4:109642688-109649496 (-)
C3H/HeJ ENSMUSG00175039089
 protein coding gene Chr4:110657109-110663917 (-)
C57BL/6NJ ENSMUSG00215031549
 protein coding gene Chr4:111732689-111739497 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026333
 protein coding gene Chr4:106988887-106992952 (-)
CAST/EiJ ENSTCUG00005019395
 protein coding gene Chr4:110426089-110430175 (-)
CBA/J ENSMUSG00210052970
 protein coding gene Chr4:110270590-110277398 (-)
DBA/2J ENSMUSG00185048098
 protein coding gene Chr4:111795223-111802031 (-)
FVB/NJ ENSMUSG00205042275
 protein coding gene Chr4:109740157-109746965 (-)
JF1/MsJ ENSUMUG00000019958
 protein coding gene Chr4:111697256-111701342 (-)
LP/J ENSMUSG00230045356
 protein coding gene Chr4:115122028-115128836 (-)
NOD/ShiLtJ ENSMUSG00190045872
 protein coding gene Chr4:109638960-109645768 (-)
NZO/HlLtJ ENSMUSG00225009882
 protein coding gene Chr4:120604400-120611210 (-)
PWK/PhJ ENSLUMG00010044836
 protein coding gene Chr4:109097277-109100437 (-)
SPRET/EiJ ENSMSPG00010027854
 protein coding gene Chr4:111201160-111204658 (-)
WSB/EiJ ENSIUOG00005042940
 protein coding gene Chr4:109957776-109964584 (-)



Homology
more
  • Human Ortholog
    TMEM69, transmembrane protein 69
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM69, transmembrane protein 69
  • Synonyms
    C1orf154
  • Links
    NCBI Gene ID: 51249
    UniProt: Q5SWH9

  • Chr Location
    1p34.1; chr1:45688149-45694443 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055900 Ensembl Gene Model | MGI Sequence Detail 4031 C57BL/6J ±  kb
transcript ENSMUST00000069674 Ensembl | MGI Sequence Detail 974 Not Applicable  
polypeptide ENSMUSP00000065821 Ensembl | MGI Sequence Detail 245 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 6
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:148802 Boles MK, et al., A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009;10:12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory