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Igfn1 Gene Detail
Summary
  • Symbol
    Igfn1
  • Name
    immunoglobulin-like and fibronectin type III domain containing 1
  • Synonyms
    9830123M21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045352
    NCBI Gene: 226438
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135881316-135934080 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 59.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1822 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045352
 protein coding gene Chr1:135880943-135968663 (-)
129S1/SvImJ ENSMUSG00200006965
 protein coding gene Chr1:133496233-133549131 (-)
A/J ENSMUSG00195015355
 protein coding gene Chr1:132568677-132621474 (-)
AKR/J ENSMUSG00220002636
 protein coding gene Chr1:132459588-132512363 (-)
BALB/cJ ENSMUSG00180011113
 protein coding gene Chr1:133109259-133162041 (-)
C3H/HeJ ENSMUSG00175006422
 protein coding gene Chr1:132812757-132865535 (-)
C57BL/6NJ ENSMUSG00215011785
 protein coding gene Chr1:132811120-132863896 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014647
 protein coding gene Chr1:127563886-127616587 (-)
CAST/EiJ ENSTCUG00005031714
 protein coding gene Chr1:131742147-131795568 (-)
CBA/J ENSMUSG00210013908
 protein coding gene Chr1:132743089-132795875 (-)
DBA/2J ENSMUSG00185028861
 protein coding gene Chr1:137119732-137172968 (-)
FVB/NJ ENSMUSG00205002177
 protein coding gene Chr1:132078789-132131569 (-)
JF1/MsJ ENSUMUG00000044404
 protein coding gene Chr1:136243743-136296904 (-)
LP/J ENSMUSG00230038418
 protein coding gene Chr1:136643901-136696674 (-)
NOD/ShiLtJ ENSMUSG00190002676
 protein coding gene Chr1:132757126-132809902 (-)
NZO/HlLtJ ENSMUSG00225019696
 protein coding gene Chr1:140410899-140463669 (-)
PWK/PhJ ENSLUMG00010001724
 protein coding gene Chr1:131868673-131921805 (-)
SPRET/EiJ ENSMSPG00010011665
 protein coding gene Chr1:134668754-134721763 (-)
WSB/EiJ ENSIUOG00005027342
 protein coding gene Chr1:132526689-132579530 (-)



Homology
more
  • Human Ortholog
    IGFN1, immunoglobulin like and fibronectin type III domain containing 1
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGFN1, immunoglobulin like and fibronectin type III domain containing 1
  • Synonyms
    EEF1A2BP1
  • Links
    NCBI Gene ID: 91156
    UniProt: Q86VF2

  • Chr Location
    1q32.1; chr1:201190824-201228952 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Homozygous mutant mice are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    5
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051985 Ensembl Gene Model | MGI Sequence Detail 52765 C57BL/6J ±  kb
transcript ENSMUST00000166193 Ensembl | MGI Sequence Detail 8989 Not Applicable  
polypeptide ENSMUSP00000129680 Ensembl | MGI Sequence Detail 2849 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory