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Fbll1 Gene Detail
Summary
  • Symbol
    Fbll1
  • Name
    fibrillarin-like 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3034689
    NCBI Gene: 237730
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:35688209-35689711 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 21.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3034689
 protein coding gene Chr11:35688207-35689711 (-)
129S1/SvImJ ENSMUSG00200006824
 protein coding gene Chr11:32742834-32744336 (-)
A/J ENSMUSG00195006949
 protein coding gene Chr11:32667850-32669352 (-)
AKR/J ENSMUSG00220003058
 protein coding gene Chr11:32853504-32855006 (-)
BALB/cJ ENSMUSG00180001656
 protein coding gene Chr11:32667980-32669482 (-)
C3H/HeJ ENSMUSG00175003581
 protein coding gene Chr11:32637678-32639180 (-)
C57BL/6NJ ENSMUSG00215009688
 protein coding gene Chr11:32591894-32593396 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016207
 protein coding gene Chr11:31377761-31379245 (-)
CAST/EiJ ENSTCUG00005013006
 protein coding gene Chr11:32499725-32501219 (-)
CBA/J ENSMUSG00210006555
 protein coding gene Chr11:32523904-32525406 (-)
DBA/2J ENSMUSG00185009998
 protein coding gene Chr11:32717005-32718507 (-)
FVB/NJ ENSMUSG00205011000
 protein coding gene Chr11:32763400-32764902 (-)
JF1/MsJ ENSUMUG00000004808
 protein coding gene Chr11:33034534-33036037 (-)
LP/J ENSMUSG00230003007
 protein coding gene Chr11:33888089-33889591 (-)
NOD/ShiLtJ ENSMUSG00190007213
 protein coding gene Chr11:32784378-32785881 (-)
NZO/HlLtJ ENSMUSG00225030221
 protein coding gene Chr11:35827421-35828924 (-)
PWK/PhJ ENSLUMG00010007166
 protein coding gene Chr11:32605473-32606966 (-)
SPRET/EiJ ENSMSPG00010002228
 protein coding gene Chr11:32986146-32987636 (-)
WSB/EiJ ENSIUOG00005002019
 protein coding gene Chr11:32690608-32692110 (-)



Homology
more
  • Human Ortholog
    FBLL1, fibrillarin like rRNA 2'-O-methyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBLL1, fibrillarin like rRNA 2'-O-methyltransferase 1
  • Links
    NCBI Gene ID: 345630
    UniProt: A6NHQ2

  • Chr Location
    5q34; chr5:168529305-168530634 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    603
  • Tissues
    6
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051062 Ensembl Gene Model | MGI Sequence Detail 1503 C57BL/6J ±  kb
transcript ENSMUST00000160726 Ensembl | MGI Sequence Detail 1503 Not Applicable  
polypeptide ENSMUSP00000128889 Ensembl | MGI Sequence Detail 314 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:362051 Zhang D, et al., Identification of FBLL1 as a neuron-specific RNA 2'-O-methyltransferase mediating neuronal differentiation. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2406961121
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory