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Mrgprb3 Gene Detail
Summary
  • Symbol
    Mrgprb3
  • Name
    MAS-related GPR, member B3
  • Synonyms
    MrgB3
Location &
Maps
more
  • Sequence Map
    Chr7:48292611-48293549 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 31.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3033117
 protein coding gene Chr7:48292551-48293559 (-)
129S1/SvImJ ENSMUSG00200023362
 protein coding gene Chr7:35918767-35919775 (-)
A/J ENSMUSG00195045446
 protein coding gene Chr7:39922995-39924003 (-)
AKR/J ENSMUSG00220008160
 protein coding gene Chr7:34212837-34213845 (-)
BALB/cJ ENSMUSG00180033523
 protein coding gene Chr7:36806782-36807790 (-)
C3H/HeJ ENSMUSG00175027725
 protein coding gene Chr7:37380227-37381235 (-)
C57BL/6NJ ENSMUSG00215039093
 protein coding gene Chr7:36589744-36590752 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029783
 protein coding gene Chr7:51761333-51762341 (-)
CAST/EiJ ENSTCUG00005022371
 protein coding gene Chr7:40431213-40432221 (-)
CBA/J ENSMUSG00210036215
 protein coding gene Chr7:37691417-37692425 (-)
DBA/2J ENSMUSG00185027786
 protein coding gene Chr7:41589777-41590785 (-)
FVB/NJ ENSMUSG00205045723
 protein coding gene Chr7:37329135-37330143 (-)
JF1/MsJ ENSUMUG00000051316
 protein coding gene Chr7:46351086-46352094 (-)
LP/J ENSMUSG00230051344
 protein coding gene Chr7:47103731-47104739 (-)
NOD/ShiLtJ ENSMUSG00190046385
 protein coding gene Chr7:37669916-37670924 (-)
NZO/HlLtJ ENSMUSG00225012543
 protein coding gene Chr7:45217188-45218196 (-)
PWK/PhJ ENSLUMG00010041058
 protein coding gene Chr7:36447323-36448331 (-)
SPRET/EiJ ENSMSPG00010035941
 protein coding gene Chr7:36281605-36282613 (-)
WSB/EiJ ENSIUOG00005026838
 protein coding gene Chr7:38020370-38021378 (-)



Homology
more
  • Human Ortholog
    MRGPRX2, MAS related GPR family member X2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRGPRX2, MAS related GPR family member X2
  • Synonyms
    MGRG3, MRGX2
  • Links
    NCBI Gene ID: 117194
    UniProt: Q96LB1

  • Chr Location
    11p15.1; chr11:19054455-19060717 (-)  GRCh38
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
  • Synonyms
    GPCR, MRGX3, SNSR1, SNSR2
  • Links
    NCBI Gene ID: 117195
    UniProt: Q96LB0

  • Chr Location
    11p15.1; chr11:18120955-18138488 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 404238 NCBI Gene Model | MGI Sequence Detail 939 C57BL/6J ±  kb
transcript NM_207537 RefSeq | MGI Sequence Detail 939 C57BL/6  
polypeptide Q91ZC1 UniProt | EBI | MGI Sequence Detail 312 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR026234 Mas-related G protein-coupled receptor family
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory