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Sbk3 Gene Detail
Summary
  • Symbol
    Sbk3
  • Name
    SH3 domain binding kinase family, member 3
  • Synonyms
    Gm1078, LOC381835
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685924
    NCBI Gene: 381835
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4968259-4974878 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685924
 protein coding gene Chr7:4968246-4995756 (-)
129S1/SvImJ ENSMUSG00200040297
 protein coding gene Chr7:1698579-1704653 (-)
A/J ENSMUSG00195050775
 protein coding gene Chr7:1689399-1695473 (-)
AKR/J ENSMUSG00220022737
 protein coding gene Chr7:2399751-2405825 (+)
BALB/cJ ENSMUSG00180042508
 protein coding gene Chr7:1644611-1650685 (-)
C3H/HeJ ENSMUSG00175041853
 protein coding gene Chr7:1652295-1658369 (-)
C57BL/6NJ ENSMUSG00215041757
 protein coding gene Chr7:1691081-1696989 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029139
 protein coding gene Chr7:1644367-1650284 (-)
CAST/EiJ ENSTCUG00005024086
 protein coding gene Chr7:1862064-1867927 (-)
CBA/J ENSMUSG00210042700
 protein coding gene Chr7:1650754-1656828 (-)
DBA/2J ENSMUSG00185042862
 protein coding gene Chr7:1833200-1839276 (-)
FVB/NJ ENSMUSG00205043831
 protein coding gene Chr7:1631362-1637439 (-)
JF1/MsJ ENSUMUG00000034148
 protein coding gene Chr7:1900073-1905963 (-)
LP/J ENSMUSG00230038720
 protein coding gene Chr7:4844031-4850105 (-)
NOD/ShiLtJ ENSMUSG00190040131
 protein coding gene Chr7:1723193-1729268 (-)
NZO/HlLtJ ENSMUSG00225020549
 protein coding gene Chr7:2757330-2763242 (-)
PWK/PhJ ENSLUMG00010045869
 protein coding gene Chr7:5412673-5418556 (-)
SPRET/EiJ ENSMSPG00010046156
 protein coding gene Chr7:1823483-1829329 (-)
WSB/EiJ ENSIUOG00005047110
 protein coding gene Chr7:1651233-1657138 (-)



Homology
more
  • Human Ortholog
    SBK3, SH3 domain binding kinase family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SBK3, SH3 domain binding kinase family member 3
  • Synonyms
    SGK110
  • Links
    NCBI Gene ID: 100130827
    UniProt: P0C264

  • Chr Location
    19q13.42; chr19:55539018-55550284 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000085272 Ensembl Gene Model | MGI Sequence Detail 6620 C57BL/6J ±  kb
transcript ENSMUST00000133272 Ensembl | MGI Sequence Detail 1797 Not Applicable  
polypeptide ENSMUSP00000120654 Ensembl | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:91783 Caenepeel S, et al., The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11707-12
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory