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Trim75 Gene Detail
Summary
  • Symbol
    Trim75
  • Name
    tripartite motif-containing 75
  • Synonyms
    LOC333307
Location &
Maps
more
  • Sequence Map
    Chr8:65434303-65440296 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 32.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    286 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685640
 protein coding gene Chr8:65433536-65440483 (-)
129S1/SvImJ ENSMUSG00200032393
 protein coding gene Chr8:60265998-60272945 (-)
A/J ENSMUSG00195011794
 protein coding gene Chr8:60621404-60628351 (-)
AKR/J ENSMUSG00220005305
 protein coding gene Chr8:60453718-60460664 (-)
BALB/cJ ENSMUSG00180013846
 protein coding gene Chr8:60245010-60251956 (-)
C3H/HeJ ENSMUSG00175019050
 protein coding gene Chr8:60469910-60476856 (-)
C57BL/6NJ ENSMUSG00215022309
 protein coding gene Chr8:60257628-60264576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031088
 protein coding gene Chr8:57537389-57543102 (-)
CAST/EiJ ENSTCUG00005006486
 protein coding gene Chr8:60071632-60078819 (-)
CBA/J ENSMUSG00210028447
 protein coding gene Chr8:60350878-60357824 (-)
DBA/2J ENSMUSG00185022385
 protein coding gene Chr8:66403742-66410688 (-)
FVB/NJ ENSMUSG00205011242
 protein coding gene Chr8:59703571-59710518 (-)
JF1/MsJ ENSUMUG00000008125
 protein coding gene Chr8:68662220-68669368 (-)
LP/J ENSMUSG00230005963
 protein coding gene Chr8:70062381-70069327 (-)
NOD/ShiLtJ ENSMUSG00190009678
 protein coding gene Chr8:60227762-60234708 (-)
NZO/HlLtJ ENSMUSG00225047676
 protein coding gene Chr8:73475216-73482158 (-)
PWK/PhJ ENSLUMG00010012848
 protein coding gene Chr8:60143855-60150818 (-)
SPRET/EiJ ENSMSPG00010030733
 protein coding gene Chr8:61415144-61418519 (-)
WSB/EiJ ENSIUOG00005025465
 protein coding gene Chr8:61149318-61156265 (-)



Homology
more
  • Human Ortholog
    TRIM75, tripartite motif containing 75
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM75, tripartite motif containing 75
  • Synonyms
    TRIM75P
  • Links
    NCBI Gene ID: 391714
    UniProt: A6NK02

  • Chr Location
    4q32.3; chr4:165053866-165060554 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 333307 NCBI Gene Model | MGI Sequence Detail 5994 C57BL/6J ±  kb
transcript NM_001033429 RefSeq | MGI Sequence Detail 2504 C57BL/6  
polypeptide Q3UWZ0 UniProt | EBI | MGI Sequence Detail 467 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:380811 Lou X, et al., Structural studies of the coiled-coil domain of TRIM75 reveal a tetramer architecture facilitating its E3 ligase complex. Comput Struct Biotechnol J. 2022;20:4921-4929
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory