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Clpsl2 Gene Detail
Summary
  • Symbol
    Clpsl2
  • Name
    colipase-like 2
  • Synonyms
    Gm749, LOC328788
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685595
    NCBI Gene: 328788
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28768461-28771592 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685595
protein coding gene Chr17:28768385-28771594 (+)
129S1/SvImJ ENSMUSG00200048356
protein coding gene Chr17:24426684-24429891 (+)
A/J ENSMUSG00195052195
protein coding gene Chr17:25243038-25246248 (+)
AKR/J ENSMUSG00220050563
protein coding gene Chr17:24290684-24293893 (+)
BALB/cJ ENSMUSG00180042138
protein coding gene Chr17:24729166-24732375 (+)
C3H/HeJ ENSMUSG00175050435
protein coding gene Chr17:24279099-24282311 (+)
C57BL/6NJ ENSMUSG00215053616
protein coding gene Chr17:24279156-24282366 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021323
protein coding gene Chr17:24400136-24403784 (+)
CAST/EiJ ENSTCUG00005044254
protein coding gene Chr17:25022695-25025961 (+)
CBA/J ENSMUSG00210041894
protein coding gene Chr17:24117533-24120742 (+)
DBA/2J ENSMUSG00185037821
protein coding gene Chr17:26332823-26336031 (+)
FVB/NJ ENSMUSG00205046462
protein coding gene Chr17:24594076-24597286 (+)
JF1/MsJ ENSUMUG00000056652
protein coding gene Chr17:25797494-25800629 (+)
LP/J ENSMUSG00230054633
protein coding gene Chr17:27852488-27855696 (+)
NOD/ShiLtJ ENSMUSG00190051805
protein coding gene Chr17:24226982-24230193 (+)
NZO/HlLtJ ENSMUSG00225051303
protein coding gene Chr17:29820431-29823640 (+)
PWK/PhJ ENSLUMG00010040053
protein coding gene Chr17:23720123-23723260 (+)
SPRET/EiJ ENSMSPG00010042902
protein coding gene Chr17:25007762-25011029 (+)
WSB/EiJ ENSIUOG00005050519
protein coding gene Chr17:24987409-24990666 (+)



Homology
more
  • Human Ortholog
    CLPSL2, colipase like 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLPSL2, colipase like 2
  • Synonyms
    AAAL3045, C6orf126, dJ510O8.5, UNQ3045
  • Links
    NCBI Gene ID: 389383
    UniProt: Q6UWE3

  • Chr Location
    6p21.31; chr6:35776535-35779557 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice exhibit normal spermatozoa and fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 328788 NCBI Gene Model | MGI Sequence Detail 3132 C57BL/6J ±  kb
    transcript NM_001034871 RefSeq | MGI Sequence Detail 444 C57BL/6  
    polypeptide Q3UW21 UniProt | EBI | MGI Sequence Detail 102 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 28
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:279041 Noda T, et al., Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice. Andrology. 2019;

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/01/2026
    MGI 6.24
    The Jackson Laboratory