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Hapstr2 Gene Detail
Summary
  • Symbol
    Hapstr2
  • Name
    HUWE1 associated protein modifying stress responses 2
  • Synonyms
    Gm715, LOC279618
Location &
Maps
more
  • Sequence Map
    ChrX:59591614-59592823 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 33.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685561
 protein coding gene ChrX:59591614-59592823 (+)
129S1/SvImJ ENSMUSG00200015765
 protein coding gene ChrX:41842849-41844058 (+)
A/J ENSMUSG00195009052
 protein coding gene ChrX:45371098-45372307 (+)
AKR/J ENSMUSG00220024171
 protein coding gene ChrX:40920190-40921399 (+)
BALB/cJ ENSMUSG00180006596
 protein coding gene ChrX:41991782-41992991 (+)
C3H/HeJ ENSMUSG00175009100
 protein coding gene ChrX:45548200-45549409 (+)
C57BL/6NJ ENSMUSG00215007052
 protein coding gene ChrX:42149011-42150220 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0012657
 pseudogene ChrX:55923664-55924494 (+)
CAST/EiJ ENSTCUG00005019338
 protein coding gene ChrX:43760171-43761380 (+)
CBA/J ENSMUSG00210018567
 protein coding gene ChrX:42351094-42352303 (+)
DBA/2J ENSMUSG00185034231
 protein coding gene ChrX:54636959-54638168 (+)
FVB/NJ ENSMUSG00205008958
 protein coding gene ChrX:41972930-41974139 (+)
JF1/MsJ ENSUMUG00000026069
 protein coding gene ChrX:75558751-75559960 (+)
LP/J ENSMUSG00230018703
 protein coding gene ChrX:61193928-61195137 (+)
NOD/ShiLtJ ENSMUSG00190012858
 protein coding gene ChrX:41641841-41643050 (+)
NZO/HlLtJ ENSMUSG00225032025
 protein coding gene ChrX:66439347-66440556 (+)
PWK/PhJ ENSLUMG00010025913
 protein coding gene ChrX:41515347-41516556 (+)
SPRET/EiJ ENSMSPG00010004576
 protein coding gene ChrX:44221055-44222264 (+)
WSB/EiJ ENSIUOG00005011916
 protein coding gene ChrX:42700525-42701734 (+)



Homology
more
  • Human Ortholog
    HAPSTR2, HUWE1 associated protein modifying stress responses 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HAPSTR2, HUWE1 associated protein modifying stress responses 2
  • Links
    NCBI Gene ID: 389895
    UniProt: A0A7P0TBJ1

  • Chr Location
    Xq27.1; chrX:140091678-140092911 (+)  GRCh38
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
  • All Sequences
    31
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 279618 NCBI Gene Model | MGI Sequence Detail 1210 C57BL/6J ±  kb
transcript NM_001271548 RefSeq | MGI Sequence Detail 1222 C57BL/6  
polypeptide A0A804C8T0 UniProt | EBI | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR040308 HUWE1-associated protein modifying stress responses
    IPR029196 HUWE1-associated protein modifying stress responses-like
  • GlyGen
    A0A804C8T0 1 site
Molecular
Reagents
less

  • Microarray probesets 2
Other
Accession IDs
less
MGI:8330123
References
more
  • Summaries
    All 14
    Gene Ontology 4
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory