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Mroh5 Gene Detail
Summary
  • Symbol
    Mroh5
  • Name
    maestro heat-like repeat family member 5
  • Synonyms
    Gm628, LOC268816
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685474
    NCBI Gene: 268816
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:73658785-73711520 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1515 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685474
 protein coding gene Chr15:73631916-73711548 (-)
129S1/SvImJ ENSMUSG00200019205
 protein coding gene Chr15:70748695-70828182 (-)
A/J ENSMUSG00195027607
 protein coding gene Chr15:70804793-70884418 (-)
AKR/J ENSMUSG00220021276
 protein coding gene Chr15:70725356-70804986 (-)
BALB/cJ ENSMUSG00180022624
 protein coding gene Chr15:70577244-70656865 (-)
C3H/HeJ ENSMUSG00175005177
 protein coding gene Chr15:70933947-71018878 (-)
C57BL/6NJ ENSMUSG00215005843
 protein coding gene Chr15:70634420-70714055 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019867
 protein coding gene Chr15:67311033-67388726 (-)
CAST/EiJ ENSTCUG00005019602
 protein coding gene Chr15:70241481-70326908 (-)
CBA/J ENSMUSG00210024471
 protein coding gene Chr15:70714582-70794204 (-)
DBA/2J ENSMUSG00185024045
 protein coding gene Chr15:70660380-70739637 (-)
FVB/NJ ENSMUSG00205010556
 protein coding gene Chr15:70398001-70477626 (-)
JF1/MsJ ENSUMUG00000014102
 protein coding gene Chr15:70312269-70391755 (-)
LP/J ENSMUSG00230051182
 protein coding gene Chr15:74024101-74103726 (-)
NOD/ShiLtJ ENSMUSG00190004301
 protein coding gene Chr15:70773790-70853047 (-)
NZO/HlLtJ ENSMUSG00225052697
 protein coding gene Chr15:74300603-74379855 (-)
PWK/PhJ ENSLUMG00010010727
 protein coding gene Chr15:70592365-70671788 (-)
SPRET/EiJ ENSMSPG00010050208
 protein coding gene Chr15:72268339-72351768 (-)
WSB/EiJ ENSIUOG00005019856
 protein coding gene Chr15:70769006-70848247 (-)



Homology
more
  • Human Ortholog
    MROH5, maestro heat like repeat family member 5 (gene/pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH5, maestro heat like repeat family member 5 (gene/pseudogene)
  • Links
    NCBI Gene ID: 389690
    UniProt: Q6ZUA9

  • Chr Location
    8q24.3; chr8:141433825-141507230 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Mroh5
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    41 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 268816 NCBI Gene Model | MGI Sequence Detail 52736 C57BL/6J ±  kb
transcript NM_001428951 RefSeq | MGI Sequence Detail 3962 C57BL/6  
polypeptide NP_001415880 RefSeq | MGI Sequence Detail 1293 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR045206 Maestro heat-like repeat-containing protein
    IPR048465 Maestro-like, HEAT-repeats domain
    IPR055406 Maestro/Maestro-like, HEAT-repeats domain
    IPR055408 MROH2B-like, HEAT-repeats domain
    IPR056282 MROH2B-like, N-terminal HEAT-repeats domain
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 8
References
more
  • Summaries
    All 46
    Diseases 1
    Gene Ontology 2
    Phenotypes 30
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory