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Fam81b Gene Detail
Summary
  • Symbol
    Fam81b
  • Name
    family with sequence similarity 81, member B
  • Synonyms
    LOC238726
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685122
    NCBI Gene: 238726
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:76349827-76427034 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 40.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685122
protein coding gene Chr13:76349827-76453191 (-)
129S1/SvImJ ENSMUSG00200005410
protein coding gene Chr13:70776068-70877202 (-)
A/J ENSMUSG00195025071
protein coding gene Chr13:71335731-71436868 (-)
AKR/J ENSMUSG00220035338
protein coding gene Chr13:69916713-70017773 (-)
BALB/cJ ENSMUSG00180001425
protein coding gene Chr13:71833967-71935103 (-)
C3H/HeJ ENSMUSG00175018271
protein coding gene Chr13:72112269-72213403 (-)
C57BL/6NJ ENSMUSG00215002492
protein coding gene Chr13:71922723-72026123 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005003940
protein coding gene Chr13:71394622-71498086 (-)
CBA/J ENSMUSG00210005379
protein coding gene Chr13:71421101-71522125 (-)
DBA/2J ENSMUSG00185017079
protein coding gene Chr13:75109201-75210235 (-)
FVB/NJ ENSMUSG00205012110
protein coding gene Chr13:70809770-70910887 (-)
JF1/MsJ ENSUMUG00000015343
protein coding gene Chr13:74864981-74971225 (-)
LP/J ENSMUSG00230026050
protein coding gene Chr13:85027690-85093232 (-)
NOD/ShiLtJ ENSMUSG00190008425
protein coding gene Chr13:71451342-71552435 (-)
NZO/HlLtJ ENSMUSG00225027802
protein coding gene Chr13:77550702-77616356 (-)
PWK/PhJ ENSLUMG00010014373
protein coding gene Chr13:70975806-71079940 (-)
SPRET/EiJ ENSMSPG00010001321
protein coding gene Chr13:71850901-71960587 (-)
WSB/EiJ ENSIUOG00005017269
protein coding gene Chr13:70659212-70758554 (-)



Homology
more
  • Human Ortholog
    FAM81B, family with sequence similarity 81 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM81B, family with sequence similarity 81 member B
  • Links
    NCBI Gene ID: 153643
    UniProt: Q96LP2

  • Chr Location
    5q15; chr5:95391366-95450454 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    • UniProt
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 238726 NCBI Gene Model | MGI Sequence Detail 77208 C57BL/6J ±  kb
    transcript NM_001370926 RefSeq | MGI Sequence Detail 1734 C57BL/6  
    polypeptide NP_001357855 RefSeq | MGI Sequence Detail 412 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR029619 Protein FAM81
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 3
    References
    more
    • Summaries
      All 23
      Developmental Gene Expression 1
      Phenotypes 8
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory