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Tmem39b Gene Detail
Summary
  • Symbol
    Tmem39b
  • Name
    transmembrane protein 39b
  • Synonyms
    6330509E05Rik, MGC:59407
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682939
    NCBI Gene: 230770
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129570148-129590631 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.31 cM, cytoband D2.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682939
protein coding gene Chr4:129570145-129595850 (-)
129S1/SvImJ ENSMUSGG00200054453
protein coding gene Chr4:123026577-123030931 (-)
129S1/SvImJ ENSMUSG00200019815
protein coding gene Chr4:123026104-123026660 (-)
A/J ENSMUSGG00195054973
protein coding gene Chr4:124362202-124366556 (-)
A/J ENSMUSG00195037306
protein coding gene Chr4:124361729-124362285 (-)
AKR/J ENSMUSGG00220054390
protein coding gene Chr4:123353954-123358308 (-)
AKR/J ENSMUSG00220046427
protein coding gene Chr4:123353481-123354037 (-)
BALB/cJ ENSMUSGG00180055076
protein coding gene Chr4:121995896-122000252 (-)
BALB/cJ ENSMUSG00180048282
protein coding gene Chr4:121995423-121995979 (-)
C3H/HeJ ENSMUSGG00175054629
protein coding gene Chr4:123008497-123012851 (-)
C3H/HeJ ENSMUSG00175044902
protein coding gene Chr4:123008024-123008580 (-)
C57BL/6NJ ENSMUSGG00215055776
protein coding gene Chr4:124510474-124514837 (-)
C57BL/6NJ ENSMUSG00215051539
protein coding gene Chr4:124510009-124510557 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026533
protein coding gene Chr4:119486909-119508926 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054979
protein coding gene Chr4:122637511-122641865 (-)
CBA/J ENSMUSG00210053742
protein coding gene Chr4:122637038-122637594 (-)
DBA/2J ENSMUSG00185051935
protein coding gene Chr4:124169387-124169943 (-)
DBA/2J ENSMUSGG00185057877
protein coding gene Chr4:124169860-124174215 (-)
FVB/NJ ENSMUSG00205041317
protein coding gene Chr4:122395954-122396510 (-)
FVB/NJ ENSMUSGG00205054601
protein coding gene Chr4:122396427-122400780 (-)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055786
protein coding gene Chr4:127964012-127968365 (-)
LP/J ENSMUSG00230033790
protein coding gene Chr4:127963539-127964095 (-)
NOD/ShiLtJ ENSMUSGG00190055060
protein coding gene Chr4:122401399-122405756 (-)
NOD/ShiLtJ ENSMUSG00190044258
protein coding gene Chr4:122400926-122401482 (-)
NZO/HlLtJ ENSMUSG00225024963
protein coding gene Chr4:133880290-133880846 (-)
NZO/HlLtJ ENSMUSGG00225055695
protein coding gene Chr4:133880763-133885117 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TMEM39B, transmembrane protein 39B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM39B, transmembrane protein 39B
  • Links
    NCBI Gene ID: 55116
    UniProt: Q9GZU3

  • Chr Location
    1p35.2; chr1:32072031-32102866 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053730 Ensembl Gene Model | MGI Sequence Detail 20484 C57BL/6J ±  kb
transcript ENSMUST00000102588 Ensembl | MGI Sequence Detail 1810 Not Applicable  
polypeptide ENSMUSP00000099648 Ensembl | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 1
Other
Accession IDs
less
MGI:1923394
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory