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Tent4a Gene Detail
Summary
  • Symbol
    Tent4a
  • Name
    terminal nucleotidyltransferase 4A
  • Synonyms
    LAK-1, MGC:69673, Papd7, Pols, TRF4, TRF4-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682295
    NCBI Gene: 210106
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:69646071-69682710 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 35.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    841 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682295
 protein coding gene Chr13:69646071-69682736 (-)
129S1/SvImJ ENSMUSG00200011344
 protein coding gene Chr13:64009231-64045687 (-)
A/J ENSMUSG00195026583
 protein coding gene Chr13:64630798-64667243 (-)
AKR/J ENSMUSG00220035768
 protein coding gene Chr13:63205526-63241981 (-)
BALB/cJ ENSMUSG00180024778
 protein coding gene Chr13:65115849-65152285 (-)
C3H/HeJ ENSMUSG00175008191
 protein coding gene Chr13:65416439-65452892 (-)
C57BL/6NJ ENSMUSG00215010818
 protein coding gene Chr13:65172656-65209319 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018689
 protein coding gene Chr13:64240904-64277995 (-)
CAST/EiJ ENSTCUG00005011456
 protein coding gene Chr13:64752806-64789799 (-)
CBA/J ENSMUSG00210009169
 protein coding gene Chr13:64739311-64775762 (-)
DBA/2J ENSMUSG00185008407
 protein coding gene Chr13:68435599-68472045 (-)
FVB/NJ ENSMUSG00205015583
 protein coding gene Chr13:64114882-64151316 (-)
JF1/MsJ ENSUMUG00000030378
 protein coding gene Chr13:68168162-68204823 (-)
LP/J ENSMUSG00230031455
 protein coding gene Chr13:78362558-78399274 (-)
NOD/ShiLtJ ENSMUSG00190024216
 protein coding gene Chr13:64743164-64779599 (-)
NZO/HlLtJ ENSMUSG00225047127
 protein coding gene Chr13:70843871-70880616 (-)
PWK/PhJ ENSLUMG00010010094
 protein coding gene Chr13:64222138-64258672 (-)
SPRET/EiJ ENSMSPG00010029652
 protein coding gene Chr13:65130099-65166552 (-)
WSB/EiJ ENSIUOG00005019358
 protein coding gene Chr13:63632683-63669113 (-)



Homology
more
  • Human Ortholog
    TENT4A, terminal nucleotidyltransferase 4A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TENT4A, terminal nucleotidyltransferase 4A
  • Synonyms
    LAK-1, LAK1, PAPD7, POLK, POLS, TRF4, TRF4-1, TRF41, TUTASE5
  • Links
    NCBI Gene ID: 11044
    UniProt: Q5XG87

  • Chr Location
    5p15.31; chr5:6713291-6757045 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    773
  • Tissues
    67
  • cDNA Data
    96
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 210106 NCBI Gene Model | MGI Sequence Detail 36640 C57BL/6J ±  kb
    transcript NM_198600 RefSeq | MGI Sequence Detail 4583 ZRU/MplStud  
    polypeptide Q6PB75 UniProt | EBI | MGI Sequence Detail 785 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 96
      cDNA 96

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:6156421
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 9
      Phenotypes 15
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory