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Tbc1d22b Gene Detail
Summary
  • Symbol
    Tbc1d22b
  • Name
    TBC1 domain family, member 22B
  • Synonyms
    MGC:31516, MGC:61359
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681867
    NCBI Gene: 381085
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:29768765-29825868 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 15.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1754 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681867
 protein coding gene Chr17:29768759-29825872 (+)
129S1/SvImJ ENSMUSG00200053668
 protein coding gene Chr17:25423807-25480830 (+)
A/J ENSMUSG00195051458
 protein coding gene Chr17:26245030-26302158 (+)
AKR/J ENSMUSG00220049446
 protein coding gene Chr17:25292721-25349844 (+)
BALB/cJ ENSMUSG00180041317
 protein coding gene Chr17:25726359-25783390 (+)
C3H/HeJ ENSMUSG00175049876
 protein coding gene Chr17:25280940-25338065 (+)
C57BL/6NJ ENSMUSG00215051506
 protein coding gene Chr17:25284859-25341982 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021347
 protein coding gene Chr17:25418373-25478753 (+)
CAST/EiJ ENSTCUG00005046603
 protein coding gene Chr17:26007895-26065164 (+)
CBA/J ENSMUSG00210050642
 protein coding gene Chr17:25119403-25176522 (+)
DBA/2J ENSMUSG00185039401
 protein coding gene Chr17:27329961-27386990 (+)
FVB/NJ ENSMUSG00205052177
 protein coding gene Chr17:25598263-25655385 (+)
JF1/MsJ ENSUMUG00000056576
 protein coding gene Chr17:26798134-26855368 (+)
LP/J ENSMUSG00230055056
 protein coding gene Chr17:28849553-28906568 (+)
NOD/ShiLtJ ENSMUSG00190047820
 protein coding gene Chr17:25234766-25291740 (+)
NZO/HlLtJ ENSMUSG00225051428
 protein coding gene Chr17:30828201-30885415 (+)
PWK/PhJ ENSLUMG00010035080
 protein coding gene Chr17:24714201-24771440 (+)
SPRET/EiJ ENSMSPG00010049374
 protein coding gene Chr17:25997901-26054842 (+)
WSB/EiJ ENSIUOG00005041180
 protein coding gene Chr17:25994462-26051552 (+)



Homology
more
  • Human Ortholog
    TBC1D22B, TBC1 domain family member 22B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TBC1D22B, TBC1 domain family member 22B
  • Synonyms
    C6orf197
  • Links
    NCBI Gene ID: 55633
    UniProt: Q9NU19

  • Chr Location
    6p21.2; chr6:37257772-37332970 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    44
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 381085 NCBI Gene Model | MGI Sequence Detail 57104 C57BL/6J ±  kb
    transcript NR_182287 RefSeq | MGI Sequence Detail 3647 C57BL/6  
    polypeptide NP_001401270 RefSeq | MGI Sequence Detail 514 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR000195 Rab-GAP-TBC domain
      IPR035969 Rab-GAP-TBC domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 44

      Microarray probesets 2
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory