About   Help   FAQ
Tas2r125 Gene Detail
Summary
  • Symbol
    Tas2r125
  • Name
    taste receptor, type 2, member 125
  • Synonyms
    mGR25, mt2r59, T2R26, Tas2r25
Location &
Maps
more
  • Sequence Map
    Chr6:132886614-132887549 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 64.03 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    152 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681269
 protein coding gene Chr6:132886614-132887550 (+)
129S1/SvImJ ENSMUSG00200044951
 protein coding gene Chr6:130381451-130382387 (+)
A/J ENSMUSG00195030425
 protein coding gene Chr6:128965518-128966454 (-)
AKR/J ENSMUSG00220037690
 protein coding gene Chr6:127502756-127503692 (-)
BALB/cJ ENSMUSG00180032183
 protein coding gene Chr6:129033146-129034082 (-)
C3H/HeJ ENSMUSG00175037348
 protein coding gene Chr6:128982525-128983461 (-)
C57BL/6NJ ENSMUSG00215014669
 protein coding gene Chr6:129537298-129538234 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028967
 protein coding gene Chr6:129945077-129946013 (-)
CAST/EiJ ENSTCUG00005039459
 protein coding gene Chr6:129816012-129816948 (-)
CBA/J ENSMUSG00210016044
 protein coding gene Chr6:129001920-129002856 (-)
DBA/2J ENSMUSG00185036779
 protein coding gene Chr6:129700535-129701471 (-)
FVB/NJ ENSMUSG00205030401
 protein coding gene Chr6:128562861-128563797 (+)
JF1/MsJ ENSUMUG00000041095
 protein coding gene Chr6:128388899-128389835 (-)
LP/J ENSMUSG00230038200
 protein coding gene Chr6:130899318-130900254 (-)
NOD/ShiLtJ ENSMUSG00190033965
 protein coding gene Chr6:129823147-129824083 (-)
NZO/HlLtJ ENSMUSG00225007160
 protein coding gene Chr6:133720101-133721037 (-)
PWK/PhJ ENSLUMG00010039110
 protein coding gene Chr6:127519424-127520360 (-)
SPRET/EiJ ENSMSPG00010035022
 protein coding gene Chr6:131195712-131196648 (-)
WSB/EiJ ENSIUOG00005040230
 protein coding gene Chr6:130106778-130107714 (+)



Homology
more
  • Human Ortholog
    TAS2R14, taste 2 receptor member 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAS2R14, taste 2 receptor member 14
  • Synonyms
    T2R14, TRB1
  • Links
    NCBI Gene ID: 50840
    UniProt: Q9NYV8

  • Chr Location
    12p13.2; chr12:10937408-11171573 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 387352 NCBI Gene Model | MGI Sequence Detail 936 C57BL/6J ±  kb
transcript NM_207027 RefSeq | MGI Sequence Detail 936 Not Specified  
polypeptide Q7M710 UniProt | EBI | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 5
  • Earliest
    J:61076 Adler E, et al., A novel family of mammalian taste receptors. Cell. 2000 Mar 17;100(6):693-702
  • Latest
    J:391000 Narukawa M, et al., Tas2r125 functions as the main receptor for detecting bitterness of tea catechins in the oral cavity of mice. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2301-2305
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory