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Slitrk5 Gene Detail
Summary
  • Symbol
    Slitrk5
  • Name
    SLIT and NTRK-like family, member 5
  • Synonyms
    2610019D03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679448
    NCBI Gene: 75409
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:111912547-111920576 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 57.86 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679448
 protein coding gene Chr14:111912529-111920576 (+)
129S1/SvImJ ENSMUSG00200018016
 protein coding gene Chr14:100803330-100811363 (+)
A/J ENSMUSG00195004092
 protein coding gene Chr14:100581642-100589680 (+)
AKR/J ENSMUSG00220001116
 protein coding gene Chr14:100335118-100343154 (+)
BALB/cJ ENSMUSG00180010313
 protein coding gene Chr14:100063784-100071831 (+)
C3H/HeJ ENSMUSG00175013348
 protein coding gene Chr14:101994610-102002655 (+)
C57BL/6NJ ENSMUSG00215006538
 protein coding gene Chr14:100175216-100183261 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019587
 protein coding gene Chr14:101267807-101275719 (+)
CAST/EiJ ENSTCUG00005002792
 protein coding gene Chr14:101802124-101810147 (+)
CBA/J ENSMUSG00210013937
 protein coding gene Chr14:100968291-100976337 (+)
DBA/2J ENSMUSG00185021215
 protein coding gene Chr14:106119635-106127680 (+)
FVB/NJ ENSMUSG00205008154
 protein coding gene Chr14:99745371-99753407 (+)
JF1/MsJ ENSUMUG00000011683
 protein coding gene Chr14:117229533-117237557 (+)
LP/J ENSMUSG00230001662
 protein coding gene Chr14:118117224-118125247 (+)
NOD/ShiLtJ ENSMUSG00190001636
 protein coding gene Chr14:100818044-100826067 (+)
NZO/HlLtJ ENSMUSG00225021354
 protein coding gene Chr14:108126287-108134310 (+)
PWK/PhJ ENSLUMG00010001094
 protein coding gene Chr14:100088031-100096047 (+)
SPRET/EiJ ENSMSPG00010012167
 protein coding gene Chr14:104181695-104189774 (+)
WSB/EiJ ENSIUOG00005006253
 protein coding gene Chr14:99986882-99994946 (+)



Homology
more
  • Human Ortholog
    SLITRK5, SLIT and NTRK like family member 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLITRK5, SLIT and NTRK like family member 5
  • Synonyms
    bA364G4.2, LRRC11
  • Links
    NCBI Gene ID: 26050
    UniProt: O94991

  • Chr Location
    13q31.2; chr13:87671371-87696272 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele have abnormal medium spiny neuron morphology and exhibit behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    10
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    673
  • Tissues
    76
  • cDNA Data
    8
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75409 NCBI Gene Model | MGI Sequence Detail 8030 C57BL/6J ±  kb
    transcript NM_001378770 RefSeq | MGI Sequence Detail 5242 C57BL/6  
    polypeptide Q810B7 UniProt | EBI | MGI Sequence Detail 957 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 9
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1922659
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 9
      Gene Ontology 10
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:348363 Matsumoto Y, et al., Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala. Front Mol Neurosci. 2024;17:1386924
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory