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Mir216a Gene Detail
Summary
  • Symbol
    Mir216a
  • Name
    microRNA 216a
  • Synonyms
    Mirn216, Mirn216a, mmu-mir-216a
Location &
Maps
more
  • Sequence Map
    Chr11:28707012-28707083 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 16.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676892
 miRNA gene Chr11:28707012-28707083 (+)
129S1/SvImJ ENSMUSG00200010102
 miRNA gene Chr11:25739559-25739630 (+)
A/J ENSMUSG00195014420
 miRNA gene Chr11:25642147-25642218 (+)
AKR/J ENSMUSG00220008703
 miRNA gene Chr11:25823458-25823529 (+)
BALB/cJ ENSMUSG00180008218
 miRNA gene Chr11:25638563-25638634 (+)
C3H/HeJ ENSMUSG00175016872
 miRNA gene Chr11:25660292-25660363 (+)
C57BL/6NJ ENSMUSG00215011712
 miRNA gene Chr11:25610740-25610811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007089
 miRNA gene Chr11:24446162-24446233 (+)
CAST/EiJ ENSTCUG00005029704
 miRNA gene Chr11:25516677-25516748 (+)
CBA/J ENSMUSG00210010093
 miRNA gene Chr11:25625665-25625736 (+)
DBA/2J ENSMUSG00185019315
 miRNA gene Chr11:25728366-25728437 (+)
FVB/NJ ENSMUSG00205023639
 miRNA gene Chr11:25690528-25690599 (+)
JF1/MsJ ENSUMUG00000010884
 miRNA gene Chr11:25973343-25973414 (+)
LP/J ENSMUSG00230016082
 miRNA gene Chr11:26859791-26859862 (+)
NOD/ShiLtJ ENSMUSG00190025245
 miRNA gene Chr11:25831191-25831262 (+)
NZO/HlLtJ ENSMUSG00225022665
 miRNA gene Chr11:28813815-28813886 (+)
PWK/PhJ ENSLUMG00010017617
 miRNA gene Chr11:25620389-25620460 (+)
SPRET/EiJ ENSMSPG00010020907
 miRNA gene Chr11:25949293-25949364 (+)
WSB/EiJ ENSIUOG00005013505
 miRNA gene Chr11:25696917-25696988 (+)



Homology
more
  • Human Ortholog
    MIR216A, microRNA 216a
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR216A, microRNA 216a
  • Synonyms
    mir-216, MIR216, mir-216a, MIRN216, MIRN216A, miRNA216
  • Links
    NCBI Gene ID: 406998

  • Chr Location
    chr2:55988950-55989059 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    1
  • Genomic Mutations
    1 involving Mir216a
  • Find Mice (IMSR)
    1 strains or lines available
Mice homozygous for a null allele exhibit pancreatic acinar-to-ductal metaplasia in vitro and increased susceptibility to induced pancreatitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    6
  • Literature Summary
    5
Sequences &
Gene Models
less
  • All Sequences
    25
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387212 NCBI Gene Model | MGI Sequence Detail 72 C57BL/6J ±  kb
transcript NR_029797 RefSeq | MGI Sequence Detail 72 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Primer pair 1
    Other 2
Other Database
Links
less
miRBase MI0000699
References
more
  • Summaries
    All 26
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:321731 Zhang H, et al., Regulation of retinal amacrine cell generation by miR-216b and Foxn3. Development. 2022 Jan 15;149(2):dev199484
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory