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Mir142 Gene Detail
Summary
  • Symbol
    Mir142
  • Name
    microRNA 142
  • Synonyms
    miR-142, Mirn142, mmu-mir-142
Location &
Maps
more
  • Sequence Map
    Chr11:87647690-87647753 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 52.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676827
 miRNA gene Chr11:87647690-87647753 (+)
129S1/SvImJ ENSMUSG00200020576
 miRNA gene Chr11:84777193-84777256 (+)
A/J ENSMUSG00195009683
 miRNA gene Chr11:84632069-84632132 (+)
AKR/J ENSMUSG00220012338
 miRNA gene Chr11:84831615-84831678 (+)
BALB/cJ ENSMUSG00180012045
 miRNA gene Chr11:84838841-84838904 (+)
C3H/HeJ ENSMUSG00175032993
 miRNA gene Chr11:84778641-84778704 (+)
C57BL/6NJ ENSMUSG00215033640
 miRNA gene Chr11:84423344-84423407 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007151
 miRNA gene Chr11:82970364-82970427 (+)
CAST/EiJ ENSTCUG00005017625
 miRNA gene Chr11:84332760-84332823 (+)
CBA/J ENSMUSG00210040673
 miRNA gene Chr11:84596185-84596248 (+)
DBA/2J ENSMUSG00185020332
 miRNA gene Chr11:84912908-84912971 (+)
FVB/NJ ENSMUSG00205022269
 miRNA gene Chr11:84791824-84791887 (+)
JF1/MsJ ENSUMUG00000031223
 miRNA gene Chr11:85237248-85237311 (+)
LP/J ENSMUSG00230030376
 miRNA gene Chr11:85946155-85946218 (+)
NOD/ShiLtJ ENSMUSG00190019928
 miRNA gene Chr11:84944201-84944264 (+)
NZO/HlLtJ ENSMUSG00225039706
 miRNA gene Chr11:88062068-88062131 (+)
PWK/PhJ ENSLUMG00010033098
 miRNA gene Chr11:84795917-84795980 (+)
SPRET/EiJ ENSMSPG00010028775
 miRNA gene Chr11:85194142-85194205 (+)
WSB/EiJ ENSIUOG00005008153
 miRNA gene Chr11:84750695-84750758 (+)



Homology
more
  • Human Ortholog
    MIR142, microRNA 142
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR142, microRNA 142
  • Synonyms
    mir-142, MIRN142
  • Links
    NCBI Gene ID: 406934

  • Chr Location
    chr17:58331232-58331318 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    21
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    9
  • Targeted
    11
  • Genomic Mutations
    2 involving Mir142
  • Find Mice (IMSR)
    7 strains or lines available
Mice homozygous for a knock-out allele exhibit reduced stimulated mast cell degranulation and impaired hematopoietic lineage formation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    12
  • Literature Summary
    13
Sequences &
Gene Models
less
  • All Sequences
    26
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387160 NCBI Gene Model | MGI Sequence Detail 64 C57BL/6J ±  kb
transcript NR_029555 RefSeq | MGI Sequence Detail 64 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 10
    Primer pair 4
    Other 6
Other Database
Links
less
miRBase MI0000167
References
more
  • Summaries
    All 86
    Developmental Gene Expression 13
    Gene Ontology 5
    Phenotypes 32
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:392354 Harada K, et al., MicroRNA-142 improves IL1RAP CAR-T cell activity in acute myeloid leukemia. J Hematol Oncol. 2025 Nov 12;18(1):99
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory