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Bicral Gene Detail
Summary
  • Symbol
    Bicral
  • Name
    BRD4 interacting chromatin remodeling complex associated protein like
  • Synonyms
    BC032203, Gltscr1l, mKIAA0240
  • Feature Type
    protein coding gene
  • IDs
    MGI:2673855
    NCBI Gene: 210982
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:47109046-47169408 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1951 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2673855
 protein coding gene Chr17:47109046-47201329 (-)
129S1/SvImJ ENSMUSG00200025391
 protein coding gene Chr17:42307447-42367779 (-)
A/J ENSMUSG00195018204
 protein coding gene Chr17:43812474-43872860 (-)
AKR/J ENSMUSG00220035233
 protein coding gene Chr17:42806323-42866675 (-)
BALB/cJ ENSMUSG00180019856
 protein coding gene Chr17:43562652-43623003 (-)
C3H/HeJ ENSMUSG00175014859
 protein coding gene Chr17:42876540-42936914 (-)
C57BL/6NJ ENSMUSG00215015377
 protein coding gene Chr17:42431901-42492275 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021690
 protein coding gene Chr17:43507000-43540153 (-)
CAST/EiJ ENSTCUG00005022958
 protein coding gene Chr17:43594282-43655985 (-)
CBA/J ENSMUSG00210031390
 protein coding gene Chr17:42626231-42686589 (-)
DBA/2J ENSMUSG00185026775
 protein coding gene Chr17:45531640-45592004 (-)
FVB/NJ ENSMUSG00205052388
 protein coding gene Chr17:43102792-43163164 (-)
JF1/MsJ ENSUMUG00000033066
 protein coding gene Chr17:45148427-45210489 (-)
LP/J ENSMUSG00230040851
 protein coding gene Chr17:46424257-46484606 (-)
NOD/ShiLtJ ENSMUSG00190015881
 protein coding gene Chr17:42511908-42573968 (-)
NZO/HlLtJ ENSMUSG00225043094
 protein coding gene Chr17:48678793-48739143 (-)
PWK/PhJ ENSLUMG00010029933
 protein coding gene Chr17:42384042-42445929 (-)
SPRET/EiJ ENSMSPG00010036753
 protein coding gene Chr17:42589142-42652031 (-)
WSB/EiJ ENSIUOG00005025712
 protein coding gene Chr17:43474839-43536401 (-)



Homology
more
  • Human Ortholog
    BICRAL, BICRA like chromatin remodeling complex associated protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BICRAL, BICRA like chromatin remodeling complex associated protein
  • Synonyms
    GLTSCR1L, KIAA0240, SMARCK2
  • Links
    NCBI Gene ID: 23506
    UniProt: Q6AI39

  • Chr Location
    6p21.1; chr6:42746339-42868560 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 3 alleles in 3 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele display abnormal embryo turning, embryonic growth retardation, cardiac hypertrophy, and complete embryonic lethality during organogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    94
  • cDNA Data
    10
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036568 Ensembl Gene Model | MGI Sequence Detail 60363 C57BL/6J ±  kb
    transcript ENSMUST00000233537 Ensembl | MGI Sequence Detail 3685 Not Applicable  
    polypeptide ENSMUSP00000156590 Ensembl | MGI Sequence Detail 1074 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000059849 BRD4-interacting chromatin-remodeling complex-associated protein-like
      (term hierarchy)
    • InterPro Domains
      IPR052438 Glioma tumor suppressor candidate region 1
      IPR015671 GLTSCR protein, conserved domain
    • GlyGen
      Q8CHH5 4 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 10
      Primer pair 1
      Other 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:5883604
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory