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Gpr141 Gene Detail
Summary
  • Symbol
    Gpr141
  • Name
    G protein-coupled receptor 141
  • Synonyms
    Pgr13
  • Feature Type
    protein coding gene
  • IDs
    MGI:2672983
    NCBI Gene: 353346
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:19933852-20008427 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 7.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2672983
 protein coding gene Chr13:19933850-20008499 (-)
129S1/SvImJ ENSMUSG00200012495
 protein coding gene Chr13:17180912-17253957 (-)
A/J ENSMUSG00195033866
 protein coding gene Chr13:16297341-16369124 (-)
AKR/J ENSMUSG00220029782
 protein coding gene Chr13:16200465-16275050 (-)
BALB/cJ ENSMUSG00180031451
 protein coding gene Chr13:16657989-16729748 (-)
C3H/HeJ ENSMUSG00175028874
 protein coding gene Chr13:16730079-16804645 (-)
C57BL/6NJ ENSMUSG00215023083
 protein coding gene Chr13:16690359-16764951 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018257
 protein coding gene Chr13:15093236-15158373 (-)
CAST/EiJ ENSTCUG00005012841
 protein coding gene Chr13:16771273-16846883 (-)
CBA/J ENSMUSG00210030207
 protein coding gene Chr13:16584682-16659249 (-)
DBA/2J ENSMUSG00185012690
 protein coding gene Chr13:17286039-17360597 (-)
FVB/NJ ENSMUSG00205020699
 protein coding gene Chr13:16451097-16525488 (-)
JF1/MsJ ENSUMUG00000012383
 protein coding gene Chr13:17019426-17093547 (-)
LP/J ENSMUSG00230033441
 protein coding gene Chr13:26701238-26775798 (-)
NOD/ShiLtJ ENSMUSG00190018922
 protein coding gene Chr13:16558529-16633095 (-)
NZO/HlLtJ ENSMUSG00225045466
 protein coding gene Chr13:20453293-20527858 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010016394
 protein coding gene Chr13:15712596-15717116 (-)
WSB/EiJ ENSIUOG00005030815
 protein coding gene Chr13:15923953-15998268 (-)



Homology
more
  • Human Ortholog
    GPR141, G protein-coupled receptor 141
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR141, G protein-coupled receptor 141
  • Synonyms
    PGR13
  • Links
    NCBI Gene ID: 353345
    UniProt: Q7Z602

  • Chr Location
    7p14.1; chr7:37683721-37833788 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    646
  • Tissues
    49
  • cDNA Data
    15
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053101 Ensembl Gene Model | MGI Sequence Detail 74576 C57BL/6J ±  kb
transcript ENSMUST00000065335 Ensembl | MGI Sequence Detail 3433 Not Applicable  
polypeptide ENSMUSP00000066921 Ensembl | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:71411 Arkell RM, et al., Genetic, physical, and phenotypic characterization of the Del(13)Svea36H mouse. Mamm Genome. 2001 Sep;12(9):687-94
  • Latest
    J:350371 Sawabe A, et al., The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor. J Leukoc Biol. 2024 Apr 29;115(5):935-945
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory