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Klhdc3 Gene Detail
Summary
  • Symbol
    Klhdc3
  • Name
    kelch domain containing 3
  • Synonyms
    1300011D16Rik, Peas
  • Feature Type
    protein coding gene
  • IDs
    MGI:2651568
    NCBI Gene: 71765
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:46985476-46991840 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.90 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2651568
 protein coding gene Chr17:46985476-46991856 (-)
129S1/SvImJ ENSMUSG00200025134
 protein coding gene Chr17:42184152-42190509 (-)
A/J ENSMUSG00195017537
 protein coding gene Chr17:43688937-43695305 (-)
AKR/J ENSMUSG00220032746
 protein coding gene Chr17:42682795-42689164 (-)
BALB/cJ ENSMUSG00180018727
 protein coding gene Chr17:43439119-43445487 (-)
C3H/HeJ ENSMUSG00175014500
 protein coding gene Chr17:42753017-42759385 (-)
C57BL/6NJ ENSMUSG00215014183
 protein coding gene Chr17:42308350-42314723 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021681
 protein coding gene Chr17:43388641-43395141 (-)
CAST/EiJ ENSTCUG00005022426
 protein coding gene Chr17:43470380-43476739 (-)
CBA/J ENSMUSG00210030871
 protein coding gene Chr17:42502722-42509088 (-)
DBA/2J ENSMUSG00185028656
 protein coding gene Chr17:45408118-45414485 (-)
FVB/NJ ENSMUSG00205051424
 protein coding gene Chr17:42978829-42985195 (-)
JF1/MsJ ENSUMUG00000027998
 protein coding gene Chr17:45026684-45033051 (-)
LP/J ENSMUSG00230041209
 protein coding gene Chr17:46300510-46306878 (-)
NOD/ShiLtJ ENSMUSG00190015483
 protein coding gene Chr17:42390321-42396688 (-)
NZO/HlLtJ ENSMUSG00225042984
 protein coding gene Chr17:48555387-48561748 (-)
PWK/PhJ ENSLUMG00010029224
 protein coding gene Chr17:42262683-42269054 (-)
SPRET/EiJ ENSMSPG00010032555
 protein coding gene Chr17:42467192-42473541 (-)
WSB/EiJ ENSIUOG00005025422
 protein coding gene Chr17:43351781-43358138 (-)



Homology
more
  • Human Ortholog
    KLHDC3, kelch domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLHDC3, kelch domain containing 3
  • Synonyms
    dJ20C7.3, PEAS
  • Links
    NCBI Gene ID: 116138
    UniProt: Q9BQ90

  • Chr Location
    6p21.1; chr6:43014103-43021298 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    199
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063576 Ensembl Gene Model | MGI Sequence Detail 6365 C57BL/6J ±  kb
transcript ENSMUST00000071841 Ensembl | MGI Sequence Detail 2100 Not Applicable  
polypeptide ENSMUSP00000071743 Ensembl | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 199
    cDNA 199

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919015
References
more
  • Summaries
    All 34
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:389052 Buco PAV, et al., Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication. EMBO Rep. 2026 Apr;27(7):1759-1788
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory