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Fam168b Gene Detail
Summary
  • Symbol
    Fam168b
  • Name
    family with sequence similarity 168, member B
  • Synonyms
    MGC:58017
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448487
    NCBI Gene: 214469
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:34852307-34882094 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 13.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    736 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448487
 protein coding gene Chr1:34852300-34882146 (-)
129S1/SvImJ ENSMUSG00200003160
 protein coding gene Chr1:32389530-32419419 (-)
A/J ENSMUSG00195038640
 protein coding gene Chr1:32059610-32089497 (-)
AKR/J ENSMUSG00220008706
 protein coding gene Chr1:32077526-32107409 (-)
BALB/cJ ENSMUSG00180010842
 protein coding gene Chr1:32183157-32213005 (-)
C3H/HeJ ENSMUSG00175001341
 protein coding gene Chr1:32063870-32093755 (-)
C57BL/6NJ ENSMUSG00215022374
 protein coding gene Chr1:32160164-32190010 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014028
 protein coding gene Chr1:29547848-29577676 (-)
CAST/EiJ ENSTCUG00005002914
 protein coding gene Chr1:32213590-32243498 (-)
CBA/J ENSMUSG00210004976
 protein coding gene Chr1:31901415-31931295 (-)
DBA/2J ENSMUSG00185010810
 protein coding gene Chr1:32986755-33016640 (-)
FVB/NJ ENSMUSG00205025783
 protein coding gene Chr1:32089338-32119228 (-)
JF1/MsJ ENSUMUG00000023902
 protein coding gene Chr1:32186274-32216177 (-)
LP/J ENSMUSG00230020385
 protein coding gene Chr1:33031660-33061551 (-)
NOD/ShiLtJ ENSMUSG00190037142
 protein coding gene Chr1:32085985-32115853 (-)
NZO/HlLtJ ENSMUSG00225014031
 protein coding gene Chr1:36294118-36324002 (-)
PWK/PhJ ENSLUMG00010031597
 protein coding gene Chr1:31750936-31780805 (-)
SPRET/EiJ ENSMSPG00010023551
 protein coding gene Chr1:33182428-33207119 (-)
WSB/EiJ ENSIUOG00005036404
 protein coding gene Chr1:32063714-32093596 (-)



Homology
more
  • Human Ortholog
    FAM168B, family with sequence similarity 168 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM168B, family with sequence similarity 168 member B
  • Synonyms
    MANI
  • Links
    NCBI Gene ID: 130074
    UniProt: A1KXE4

  • Chr Location
    2q21.1; chr2:131047876-131093487 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    392
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 214469 NCBI Gene Model | MGI Sequence Detail 29788 C57BL/6J ±  kb
transcript NM_001403152 RefSeq | MGI Sequence Detail 5035 C57BL/6  
polypeptide Q80XQ8 UniProt | EBI | MGI Sequence Detail 194 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 392
    cDNA 392

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:322597 Mishra M, et al., The novel protein MANI modulates neurogenesis and neurite-cone growth. J Cell Mol Med. 2011 Aug;15(8):1713-25
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory