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Spryd3 Gene Detail
Summary
  • Symbol
    Spryd3
  • Name
    SPRY domain containing 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446175
    NCBI Gene: 223918
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102024963-102044669 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    520 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446175
 protein coding gene Chr15:102024961-102044678 (-)
129S1/SvImJ ENSMUSG00200050389
 protein coding gene Chr15:99249424-99270526 (-)
A/J ENSMUSG00195039368
 protein coding gene Chr15:99140711-99160461 (-)
AKR/J ENSMUSG00220048307
 protein coding gene Chr15:99109246-99130349 (-)
BALB/cJ ENSMUSG00180042361
 protein coding gene Chr15:99021247-99042352 (-)
C3H/HeJ ENSMUSG00175041533
 protein coding gene Chr15:99342626-99362367 (-)
C57BL/6NJ ENSMUSG00215049618
 protein coding gene Chr15:99064717-99085820 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020337
 protein coding gene Chr15:95951736-95970436 (-)
CAST/EiJ ENSTCUG00005041580
 protein coding gene Chr15:98545375-98565120 (-)
CBA/J ENSMUSG00210025834
 protein coding gene Chr15:99093807-99113548 (-)
DBA/2J ENSMUSG00185037708
 protein coding gene Chr15:99109161-99130264 (-)
FVB/NJ ENSMUSG00205025547
 protein coding gene Chr15:98813647-98834750 (-)
JF1/MsJ ENSUMUG00000029064
 protein coding gene Chr15:98569593-98589643 (-)
LP/J ENSMUSG00230035789
 protein coding gene Chr15:102470490-102491591 (-)
NOD/ShiLtJ ENSMUSG00190043326
 protein coding gene Chr15:99053959-99075094 (-)
NZO/HlLtJ ENSMUSG00225027052
 protein coding gene Chr15:102650488-102671588 (-)
PWK/PhJ ENSLUMG00010044896
 protein coding gene Chr15:98781946-98801711 (-)
SPRET/EiJ ENSMSPG00010046200
 protein coding gene Chr15:100573473-100593311 (-)
WSB/EiJ ENSIUOG00005031388
 protein coding gene Chr15:99199832-99219566 (-)



Homology
more
  • Human Ortholog
    SPRYD3, SPRY domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPRYD3, SPRY domain containing 3
  • Links
    NCBI Gene ID: 84926
    UniProt: Q8NCJ5

  • Chr Location
    12q13.13; chr12:53064316-53079414 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 2 alleles in 2 genetic backgrounds
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    40
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036966 Ensembl Gene Model | MGI Sequence Detail 19707 C57BL/6J ±  kb
    transcript ENSMUST00000154032 Ensembl | MGI Sequence Detail 2456 Not Applicable  
    polypeptide ENSMUSP00000121493 Ensembl | MGI Sequence Detail 442 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR001870 B30.2/SPRY domain
      IPR043136 B30.2/SPRY domain superfamily
      IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
      IPR003877 SPRY domain
      IPR035783 SPRY domain-containing protein 3, SPRY domain
      IPR050618 Ubiquitination and Signaling Pathway Regulator
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 40

      Microarray probesets 3
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 1
      Phenotypes 30
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory