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Marchf9 Gene Detail
Summary
  • Symbol
    Marchf9
  • Name
    membrane associated ring-CH-type finger 9
  • Synonyms
    March9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446144
    NCBI Gene: 216438
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:126891919-126896053 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 74.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446144
 protein coding gene Chr10:126890880-126896053 (-)
129S1/SvImJ ENSMUSG00200011395
 protein coding gene Chr10:123243624-123248798 (-)
A/J ENSMUSG00195014984
 protein coding gene Chr10:123707934-123713106 (-)
AKR/J ENSMUSG00220005599
 protein coding gene Chr10:123312234-123317408 (-)
BALB/cJ ENSMUSG00180009530
 protein coding gene Chr10:123699019-123704192 (-)
C3H/HeJ ENSMUSG00175005771
 protein coding gene Chr10:123696928-123701935 (-)
C57BL/6NJ ENSMUSG00215007798
 protein coding gene Chr10:123309048-123314222 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015877
 protein coding gene Chr10:119422663-119427803 (-)
CAST/EiJ ENSTCUG00005041110
 protein coding gene Chr10:122666343-122671523 (-)
CBA/J ENSMUSG00210007903
 protein coding gene Chr10:123521099-123526106 (-)
DBA/2J ENSMUSG00185026717
 protein coding gene Chr10:123667365-123672539 (-)
FVB/NJ ENSMUSG00205016605
 protein coding gene Chr10:122926703-122931876 (-)
JF1/MsJ ENSUMUG00000044455
 protein coding gene Chr10:124962833-124968010 (-)
LP/J ENSMUSG00230031419
 protein coding gene Chr10:125584415-125589589 (-)
NOD/ShiLtJ ENSMUSG00190015556
 protein coding gene Chr10:123749203-123754376 (-)
NZO/HlLtJ ENSMUSG00225037408
 protein coding gene Chr10:129791534-129796708 (-)
PWK/PhJ ENSLUMG00010009355
 protein coding gene Chr10:123421984-123427160 (-)
SPRET/EiJ ENSMSPG00010028219
 protein coding gene Chr10:125376852-125382001 (-)
WSB/EiJ ENSIUOG00005007054
 protein coding gene Chr10:123307931-123313104 (-)



Homology
more
  • Human Ortholog
    MARCHF9, membrane associated ring-CH-type finger 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MARCHF9, membrane associated ring-CH-type finger 9
  • Synonyms
    MARCH9, MARCH-IX, RNF179
  • Links
    NCBI Gene ID: 92979
    UniProt: Q86YJ5

  • Chr Location
    12q14.1; chr12:57755103-57760411 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    5
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 216438 NCBI Gene Model | MGI Sequence Detail 4135 C57BL/6J ±  kb
    transcript NM_001033262 RefSeq | MGI Sequence Detail 1998 C57BL/6  
    polypeptide Q3TZ87 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2143655, MGI:6368857
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 1
      Gene Ontology 9
      Phenotypes 10
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:376839 Gao D, et al., MARCH8 Mediates K27-Linked Polyubiquitination of IL-7 Receptor alpha to Negatively Regulate IL-7-Triggered T Cell Homeostasis. J Immunol. 2024 Nov 15;213(10):1467-1478
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory