About   Help   FAQ
Cyp4f39 Gene Detail
Summary
  • Symbol
    Cyp4f39
  • Name
    cytochrome P450, family 4, subfamily f, polypeptide 39
  • Synonyms
    4732474A20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445210
    NCBI Gene: 320997
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:32671697-32712294 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1279 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445210
 protein coding gene Chr17:32671670-32712294 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023506
 protein coding gene Chr17:32308703-32334148 (+)
A/J MGP_AJ_G0023463
 protein coding gene Chr17:31235049-31259013 (+)
AKR/J MGP_AKRJ_G0023429
 protein coding gene Chr17:31519719-31543750 (+)
BALB/cJ MGP_BALBcJ_G0023468
 protein coding gene Chr17:31332520-31360086 (+)
C3H/HeJ MGP_C3HHeJ_G0023230
 protein coding gene Chr17:31919301-31943902 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023911
 protein coding gene Chr17:33397806-33421837 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021385
 protein coding gene Chr17:28336461-28360688 (+)
CAST/EiJ MGP_CASTEiJ_G0022731
 protein coding gene Chr17:31976167-32001903 (+)
CBA/J MGP_CBAJ_G0023205
 protein coding gene Chr17:34866282-34892484 (+)
DBA/2J MGP_DBA2J_G0023335
 protein coding gene Chr17:30615188-30642874 (+)
FVB/NJ MGP_FVBNJ_G0023305
 protein coding gene Chr17:30440636-30465758 (+)
LP/J MGP_LPJ_G0023413
 protein coding gene Chr17:32524898-32549847 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023323
 protein coding gene Chr17:33934294-33958348 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023953
 protein coding gene Chr17:31887402-31912010 (+)
PWK/PhJ MGP_PWKPhJ_G0022480
 protein coding gene Chr17:29509211-29535993 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022299
 protein coding gene Chr17:29902588-29926657 (+)
WSB/EiJ MGP_WSBEiJ_G0022793
 protein coding gene Chr17:31876390-31901608 (+)



Homology
more
  • Human Ortholog
    CYP4F22, cytochrome P450 family 4 subfamily F member 22
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP4F22, cytochrome P450 family 4 subfamily F member 22
  • Synonyms
    ARCI5, INLNE, LI3
  • Links
    NCBI Gene ID: 126410
    UniProt: Q6NT55

  • Chr Location
    19p13.12; chr19:15508477-15552317 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CYP4F22 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 3 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit complete neonatal lethality associated with trans-epidermal water loss, persistent periderm, thin lipid lamella, thick corneocytes, and complete loss of acylceramide.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    8
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000061126 Ensembl Gene Model | MGI Sequence Detail 40598 C57BL/6J ±  kb
    transcript ENSMUST00000237491 Ensembl | MGI Sequence Detail 2618 Not Applicable  
    polypeptide ENSMUSP00000158442 Ensembl | MGI Sequence Detail 532 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 8
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 24
      Developmental Gene Expression 2
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:366466 Yamaji M, et al., Alteration of epidermal lipid composition as a result of deficiency in the magnesium transporter Nipal4. J Lipid Res. 2024 Apr 29;65(6):100550
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    06/09/2026
    MGI 6.24     		The Jackson Laboratory