Wscd2 MGI Mouse Gene Detail - MGI:2445030

Symbol

Wscd2
Name

WSC domain containing 2
Synonyms

4933413A10Rik, C530024P05Rik

Feature Type

protein coding gene
IDs

MGI:2445030
NCBI Gene: 320916
Alliance

genome feature page
Transcription Start Sites

13 TSS

Sequence Map

Chr5:113638199-113727786 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 55.55 cM
Mapping Data

2 experiments

SNPs within 2kb

2638 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2445030	protein coding gene	Chr5:113636976-113727786 (+)
129S1/SvImJ	ENSMUSG00200021966	protein coding gene	Chr5:107377643-107469182 (+)
A/J	ENSMUSG00195030380	protein coding gene	Chr5:106887557-106979130 (+)
AKR/J	ENSMUSG00220051312	protein coding gene	Chr5:106405816-106497344 (+)
BALB/cJ	ENSMUSG00180041127	protein coding gene	Chr5:107028082-107119613 (+)
C3H/HeJ	ENSMUSG00175042970	protein coding gene	Chr5:109006237-109098648 (+)
C57BL/6NJ	ENSMUSG00215010194	protein coding gene	Chr5:107036887-107128396 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027576	protein coding gene	Chr5:106442785-106531356 (+)
CAST/EiJ	ENSTCUG00005029043	protein coding gene	Chr5:106207058-106298777 (+)
CBA/J	ENSMUSG00210041431	protein coding gene	Chr5:107758306-107850723 (+)
DBA/2J	ENSMUSG00185044457	protein coding gene	Chr5:110812176-110903679 (+)
FVB/NJ	ENSMUSG00205024473	protein coding gene	Chr5:106665807-106757349 (+)
JF1/MsJ	ENSUMUG00000032714	protein coding gene	Chr5:113649721-113741192 (+)
LP/J	ENSMUSG00230045305	protein coding gene	Chr5:114915876-115007403 (+)
NOD/ShiLtJ	ENSMUSG00190044580	protein coding gene	Chr5:106704988-106796500 (+)
NZO/HlLtJ	ENSMUSG00225014068	protein coding gene	Chr5:122561947-122653454 (+)
PWK/PhJ	ENSLUMG00010026271	protein coding gene	Chr5:105554702-105646735 (+)
SPRET/EiJ	ENSMSPG00010043207	protein coding gene	Chr5:108880473-108919925 (+)
WSB/EiJ	ENSIUOG00005038351	protein coding gene	Chr5:109401960-109494386 (+)

Human Ortholog

WSCD2, WSC domain sialate O sulfotransferase 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

WSCD2, WSC domain sialate O sulfotransferase 2
Links

HGNC:29117

NCBI Gene ID: 9671

UniProt: Q2TBF2
Chr Location

12q23.3; chr12:108129288-108250537 (+) GRCh38

MGI Vertebrate Homology

Wscd2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: WSCD2
Gene Tree

Wscd2

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
16 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

21
Chemically induced (other)

1
Endonuclease-mediated

6
Gene trapped

12
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Wscd2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

25 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

3
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

704
Tissues

22
cDNA Data

16
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase wscd2

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All Sequences

46
RefSeq

8
UniProt

1
CCDS

CCDS19550.2

Ensembl

ENSMUSG00000063430 (Evidence)
NCBI Gene

320916

			Length	Strain/Species	Flank
genomic	ENSMUSG00000063430	Ensembl Gene Model \| MGI Sequence Detail	89588	C57BL/6J	± kb
transcript	ENSMUST00000094452	Ensembl \| MGI Sequence Detail	4302	Not Applicable
polypeptide	ENSMUSP00000092021	Ensembl \| MGI Sequence Detail	571	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000030696 sialate:O-sulfotransferase 2

(term hierarchy)
InterPro Domains

IPR002889 Carbohydrate-binding WSC

IPR027417 P-loop containing nucleoside triphosphate hydrolase

IPR051589 Sialate:O-sulfotransferase
GlyGen

D4PHA7 3 sites, 2 N-linked glycans (2 sites)

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All nucleic 16

cDNA 16

Microarray probesets 2

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MGI:2685296

Summaries

All 37

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 16
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Wscd2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr48018	Chr5:113636970-113636991 (+)	-1,218 bp
Tssr48019	Chr5:113638381-113638414 (+)	199 bp
Tssr48020	Chr5:113638446-113638464 (+)	256 bp
Tssr48021	Chr5:113638601-113638626 (+)	415 bp
Tssr48022	Chr5:113658705-113658711 (+)	20,509 bp
Tssr48023	Chr5:113658765-113658771 (+)	20,569 bp
Tssr48024	Chr5:113677108-113677114 (+)	38,912 bp
Tssr48025	Chr5:113677135-113677151 (+)	38,944 bp
Tssr1598	Chr5:113688474-113688475 (+)	50,276 bp
Tssr48026	Chr5:113688939-113688952 (+)	50,747 bp
Tssr48027	Chr5:113688967-113688984 (+)	50,777 bp
Tssr48028	Chr5:113689059-113689078 (+)	50,870 bp
Tssr48029	Chr5:113727191-113727207 (+)	89,000 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24