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Vash2 Gene Detail
Summary
  • Symbol
    Vash2
  • Name
    vasohibin 2
  • Synonyms
    B130052G07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444826
    NCBI Gene: 226841
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:190679843-190711493 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 96.28 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    867 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444826
 protein coding gene Chr1:190679843-190711500 (-)
129S1/SvImJ ENSMUSG00200003393
 protein coding gene Chr1:188459626-188491271 (-)
A/J ENSMUSG00195007951
 protein coding gene Chr1:188039537-188071180 (-)
AKR/J ENSMUSG00220004094
 protein coding gene Chr1:187283429-187315074 (-)
BALB/cJ ENSMUSG00180016133
 protein coding gene Chr1:188104971-188136611 (-)
C3H/HeJ ENSMUSG00175021912
 protein coding gene Chr1:188292972-188324618 (-)
C57BL/6NJ ENSMUSG00215011566
 protein coding gene Chr1:187512314-187543964 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015041
 protein coding gene Chr1:180759082-180785033 (-)
CAST/EiJ ENSTCUG00005001828
 protein coding gene Chr1:186070576-186102582 (-)
CBA/J ENSMUSG00210003304
 protein coding gene Chr1:187954708-187986357 (-)
DBA/2J ENSMUSG00185010152
 protein coding gene Chr1:192567954-192599603 (-)
FVB/NJ ENSMUSG00205003367
 protein coding gene Chr1:186951013-186982657 (-)
JF1/MsJ ENSUMUG00000005473
 protein coding gene Chr1:191555657-191587333 (-)
LP/J ENSMUSG00230020992
 protein coding gene Chr1:192103873-192135517 (-)
NOD/ShiLtJ ENSMUSG00190025049
 protein coding gene Chr1:187938228-187969877 (-)
NZO/HlLtJ ENSMUSG00225015284
 protein coding gene Chr1:195864889-195896534 (-)
PWK/PhJ ENSLUMG00010006192
 protein coding gene Chr1:186786930-186818575 (-)
SPRET/EiJ ENSMSPG00010022627
 protein coding gene Chr1:190328296-190359765 (-)
WSB/EiJ ENSIUOG00005004331
 protein coding gene Chr1:187291815-187323085 (-)



Homology
more
  • Human Ortholog
    VASH2, vasohibin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VASH2, vasohibin 2
  • Links
    NCBI Gene ID: 79805
    UniProt: Q86V25

  • Chr Location
    1q32.3; chr1:212950520-212992838 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice have defects in initiating angiogenesis in response to skin wounding.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    7
  • cDNA Data
    60
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037568 Ensembl Gene Model | MGI Sequence Detail 31651 C57BL/6J ±  kb
transcript ENSMUST00000166139 Ensembl | MGI Sequence Detail 3897 Not Applicable  
polypeptide ENSMUSP00000127626 Ensembl | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 60
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 12
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:322339 Yu X, et al., MARK4 controls ischaemic heart failure through microtubule detyrosination. Nature. 2021 Jun;594(7864):560-565
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory