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Bltp1 Gene Detail
Summary
  • Symbol
    Bltp1
  • Name
    bridge-like lipid transfer protein family member 1
  • Synonyms
    4932438A13Rik, B830039D19Rik, D630029K19Rik, FSA, Tweek
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444631
    NCBI Gene: 229227
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:36917253-37107182 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 18.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1549 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444631
 protein coding gene Chr3:36917212-37107182 (+)
129S1/SvImJ ENSMUSG00200005269
 protein coding gene Chr3:33676728-33860569 (+)
A/J ENSMUSG00195001366
 protein coding gene Chr3:33643464-33831009 (+)
AKR/J ENSMUSG00220000498
 protein coding gene Chr3:33696594-33891004 (+)
BALB/cJ ENSMUSG00180002376
 protein coding gene Chr3:33778496-33962138 (+)
C3H/HeJ ENSMUSG00175003262
 protein coding gene Chr3:33673526-33861063 (+)
C57BL/6NJ ENSMUSG00215001363
 protein coding gene Chr3:34052457-34236088 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024943
 protein coding gene Chr3:31691476-31883158 (+)
CAST/EiJ ENSTCUG00005000770
 protein coding gene Chr3:33519092-33707085 (+)
CBA/J ENSMUSG00210001522
 protein coding gene Chr3:33721652-33918603 (+)
DBA/2J ENSMUSG00185001190
 protein coding gene Chr3:33924816-34109961 (+)
FVB/NJ ENSMUSG00205000586
 protein coding gene Chr3:33100325-33280456 (+)
JF1/MsJ ENSUMUG00000000337
 protein coding gene Chr3:33466391-33649947 (+)
LP/J ENSMUSG00230019352
 protein coding gene Chr3:35905664-36103504 (+)
NOD/ShiLtJ ENSMUSG00190001240
 protein coding gene Chr3:33974539-34158371 (+)
NZO/HlLtJ ENSMUSG00225006815
 protein coding gene Chr3:38516231-38714383 (+)
PWK/PhJ ENSLUMG00010000522
 protein coding gene Chr3:33501143-33693418 (+)
SPRET/EiJ ENSMSPG00010000468
 protein coding gene Chr3:33886796-34084065 (+)
WSB/EiJ ENSIUOG00005012781
 protein coding gene Chr3:33970423-34165764 (+)



Homology
more
  • Human Ortholog
    BLTP1, bridge-like lipid transfer protein family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BLTP1, bridge-like lipid transfer protein family member 1
  • Synonyms
    ALKKUCS, FSA, KIAA1109, Tweek
  • Links
    NCBI Gene ID: 84162
    UniProt: Q2LD37

  • Chr Location
    4q27; chr4:122152331-122364167 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human BLTP1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 1 allele in 2 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    654
  • Tissues
    47
  • cDNA Data
    115
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037270 Ensembl Gene Model | MGI Sequence Detail 189930 C57BL/6J ±  kb
    transcript ENSMUST00000152564 Ensembl | MGI Sequence Detail 15541 Not Applicable  
    polypeptide ENSMUSP00000117808 Ensembl | MGI Sequence Detail 5005 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      10 Sequences
    • Protein Ontology
      PR:000059786 bridge-like lipid transfer protein family member 1
      (term hierarchy)
    • InterPro Domains
      IPR033616 Bridge-like lipid transfer protein family member 1
      IPR056742 Bridge-like lipid transfer protein family member 1, C-terminal
      IPR056741 Bridge-like lipid transfer protein family member 1, middle region
      IPR047104 Bridge-like lipid transfer protein family member 1, N-terminal
    • GlyGen
      A2AAE1 6 sites, 4 N-linked glycans (4 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 118
      cDNA 118

      Microarray probesets 21
    Other
    Accession IDs
    less
    MGI:2444196, MGI:2444275, MGI:7279263
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 7
      Phenotypes 21
    • Earliest
      J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
    • Latest
      J:376292 Liu Y, et al., Bltp1 Is Required for Survival and Normal Development and Function of the Neuromuscular Junction in Mice. J Neurosci. 2025 Oct 29;45(44)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory