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Slc9a7 Gene Detail
Summary
  • Symbol
    Slc9a7
  • Name
    solute carrier family 9 (sodium/hydrogen exchanger), member 7
  • Synonyms
    A530087D17Rik, NHE7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444530
    NCBI Gene: 236727
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:19971993-20158046 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 15.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4310 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444530
 protein coding gene ChrX:19965090-20158274 (-)
129S1/SvImJ ENSMUSG00200015039
 protein coding gene ChrX:14733767-14919825 (-)
A/J ENSMUSG00195007281
 protein coding gene ChrX:14734809-14920887 (-)
AKR/J ENSMUSG00220017357
 protein coding gene ChrX:14229897-14415970 (-)
BALB/cJ ENSMUSG00180021112
 protein coding gene ChrX:14668597-14854668 (-)
C3H/HeJ ENSMUSG00175028516
 protein coding gene ChrX:14709154-14895233 (-)
C57BL/6NJ ENSMUSG00215012621
 protein coding gene ChrX:15313324-15499395 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032958
 protein coding gene ChrX:13336004-13521836 (-)
CAST/EiJ ENSTCUG00005026487
 protein coding gene ChrX:14640501-14842798 (-)
CBA/J ENSMUSG00210020189
 protein coding gene ChrX:14765830-14951881 (-)
DBA/2J ENSMUSG00185030407
 protein coding gene ChrX:21366445-21552519 (-)
FVB/NJ ENSMUSG00205019443
 protein coding gene ChrX:14309231-14495305 (-)
JF1/MsJ ENSUMUG00000026249
 protein coding gene ChrX:35195121-35396008 (-)
LP/J ENSMUSG00230005806
 protein coding gene ChrX:25935845-26121904 (-)
NOD/ShiLtJ ENSMUSG00190023900
 protein coding gene ChrX:14703447-14889477 (-)
NZO/HlLtJ ENSMUSG00225041135
 protein coding gene ChrX:31175678-31361742 (-)
PWK/PhJ ENSLUMG00010016025
 protein coding gene ChrX:14602943-14802849 (-)
SPRET/EiJ ENSMSPG00010010615
 protein coding gene ChrX:15867842-16079424 (-)
WSB/EiJ ENSIUOG00005030332
 protein coding gene ChrX:11321204-11501859 (-)



Homology
more
  • Human Ortholog
    SLC9A7, solute carrier family 9 member A7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC9A7, solute carrier family 9 member A7
  • Synonyms
    MRX108, NHE-7, NHE7
  • Links
    NCBI Gene ID: 84679
    UniProt: Q96T83

  • Chr Location
    Xp11.3-p11.23; chrX:46599251-46759193 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC9A7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    620
  • Tissues
    23
  • cDNA Data
    14
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037341 Ensembl Gene Model | MGI Sequence Detail 186054 C57BL/6J ±  kb
transcript ENSMUST00000072451 Ensembl | MGI Sequence Detail 2512 Not Applicable  
polypeptide ENSMUSP00000072274 Ensembl | MGI Sequence Detail 726 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory