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Tmem278 Gene Detail
Summary
  • Symbol
    Tmem278
  • Name
    transmembrane protein 278
  • Synonyms
    A230069A22Rik, Tmem88b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444329
    NCBI Gene: 320587
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155866048-155870331 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 87.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444329
 protein coding gene Chr4:155866048-155870331 (-)
129S1/SvImJ ENSMUSG00200018507
 protein coding gene Chr4:146920833-146925113 (-)
A/J ENSMUSG00195018458
 protein coding gene Chr4:148586941-148591222 (-)
AKR/J ENSMUSG00220023920
 protein coding gene Chr4:148162337-148166617 (-)
BALB/cJ ENSMUSG00180002399
 protein coding gene Chr4:146241514-146245794 (-)
C3H/HeJ ENSMUSG00175014975
 protein coding gene Chr4:149542128-149546409 (-)
C57BL/6NJ ENSMUSG00215010716
 protein coding gene Chr4:148388835-148393122 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026902
 protein coding gene Chr4:145685247-145689530 (-)
CAST/EiJ ENSTCUG00005028574
 protein coding gene Chr4:152245799-152250141 (-)
CBA/J ENSMUSG00210004401
 protein coding gene Chr4:148200486-148204767 (-)
DBA/2J ENSMUSG00185015161
 protein coding gene Chr4:151758028-151762308 (-)
FVB/NJ ENSMUSG00205020852
 protein coding gene Chr4:146662357-146666636 (-)
JF1/MsJ ENSUMUG00000000198
 protein coding gene Chr4:154790351-154794698 (-)
LP/J ENSMUSG00230021944
 protein coding gene Chr4:158490883-158495369 (-)
NOD/ShiLtJ ENSMUSG00190003652
 protein coding gene Chr4:147866151-147870429 (-)
NZO/HlLtJ ENSMUSG00225023402
 protein coding gene Chr4:162480640-162484920 (-)
PWK/PhJ ENSLUMG00010025333
 protein coding gene Chr4:147042811-147047156 (-)
SPRET/EiJ ENSMSPG00010019613
 protein coding gene Chr4:148988185-148990288 (-)
WSB/EiJ ENSIUOG00005006039
 protein coding gene Chr4:146074796-146079082 (-)



Homology
more
  • Human Ortholog
    TMEM278, transmembrane protein 278
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM278, transmembrane protein 278
  • Synonyms
    TMEM88B
  • Links
    NCBI Gene ID: 643965
    UniProt: A6NKF7

  • Chr Location
    1p36.33; chr1:1425871-1430255 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320587 NCBI Gene Model | MGI Sequence Detail 4284 C57BL/6J ±  kb
    transcript NM_001033394 RefSeq | MGI Sequence Detail 3471 C57BL/6  
    polypeptide Q3TYP4 UniProt | EBI | MGI Sequence Detail 173 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:7864114
    References
    more
    • Summaries
      All 25
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory