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Nemp2 Gene Detail
Summary
  • Symbol
    Nemp2
  • Name
    nuclear envelope integral membrane protein 2
  • Synonyms
    5330401P04Rik, Tmem194b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444113
    NCBI Gene: 227094
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:52669862-52691078 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 26.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    880 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444113
 protein coding gene Chr1:52669850-52691078 (+)
129S1/SvImJ ENSMUSG00200001568
 protein coding gene Chr1:50144696-50165912 (+)
A/J ENSMUSG00195001854
 protein coding gene Chr1:50044538-50065755 (+)
AKR/J ENSMUSG00220003045
 protein coding gene Chr1:49801122-49822354 (+)
BALB/cJ ENSMUSG00180003011
 protein coding gene Chr1:49976753-49997988 (+)
C3H/HeJ ENSMUSG00175000058
 protein coding gene Chr1:50070784-50092000 (+)
C57BL/6NJ ENSMUSG00215002844
 protein coding gene Chr1:49997961-50019178 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014125
 protein coding gene Chr1:41448889-41467870 (-)
CAST/EiJ ENSTCUG00005000751
 protein coding gene Chr1:49898346-49919551 (+)
CBA/J ENSMUSG00210028135
 protein coding gene Chr1:49775881-49797097 (+)
DBA/2J ENSMUSG00185029052
 protein coding gene Chr1:50895512-50916728 (+)
FVB/NJ ENSMUSG00205003186
 protein coding gene Chr1:49715018-49736233 (+)
JF1/MsJ ENSUMUG00000000841
 protein coding gene Chr1:49865998-49887253 (+)
LP/J ENSMUSG00230000948
 protein coding gene Chr1:50891778-50912994 (+)
NOD/ShiLtJ ENSMUSG00190002004
 protein coding gene Chr1:49912088-49933315 (+)
NZO/HlLtJ ENSMUSG00225007554
 protein coding gene Chr1:54074115-54095320 (+)
PWK/PhJ ENSLUMG00010002416
 protein coding gene Chr1:49427094-49448353 (+)
SPRET/EiJ ENSMSPG00010021608
 protein coding gene Chr1:51119125-51146147 (+)
WSB/EiJ ENSIUOG00005003344
 protein coding gene Chr1:49616485-49637704 (+)



Homology
more
  • Human Ortholog
    NEMP2, nuclear envelope integral membrane protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NEMP2, nuclear envelope integral membrane protein 2
  • Synonyms
    TMEM194B
  • Links
    NCBI Gene ID: 100131211
    UniProt: A6NFY4

  • Chr Location
    2q32.2; chr2:190421421-190648785 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    32
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000043015 Ensembl Gene Model | MGI Sequence Detail 21217 C57BL/6J ±  kb
    transcript ENSMUST00000165859 Ensembl | MGI Sequence Detail 3396 Not Applicable  
    polypeptide ENSMUSP00000129351 Ensembl | MGI Sequence Detail 421 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      Genomic 2
      cDNA 32

      Microarray probesets 2
    References
    more
    • Summaries
      All 33
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory