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Treml6 Gene Detail
Summary
  • Symbol
    Treml6
  • Name
    triggering receptor expressed on myeloid cells-like 6
  • Synonyms
    B430306N03Rik, Trem6l
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443478
    NCBI Gene: 320148
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:48622310-48632580 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 23.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    497 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443478
 protein coding gene Chr17:48622310-48634052 (+)
129S1/SvImJ ENSMUSG00200023640
 protein coding gene Chr17:43821814-43832716 (+)
A/J ENSMUSG00195019824
 protein coding gene Chr17:45320630-45331491 (+)
AKR/J ENSMUSG00220034658
 protein coding gene Chr17:44320627-44331488 (+)
BALB/cJ ENSMUSG00180019689
 protein coding gene Chr17:45076978-45087837 (+)
C3H/HeJ ENSMUSG00175014684
 protein coding gene Chr17:44384505-44395366 (+)
C57BL/6NJ ENSMUSG00215017289
 protein coding gene Chr17:43947762-43958651 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021722
 protein coding gene Chr17:45051273-45062453 (+)
CAST/EiJ ENSTCUG00005021592
 protein coding gene Chr17:45118572-45129636 (+)
CBA/J ENSMUSG00210031828
 protein coding gene Chr17:44134091-44144944 (+)
DBA/2J ENSMUSG00185027702
 protein coding gene Chr17:47033108-47043965 (+)
FVB/NJ ENSMUSG00205022418
 protein coding gene Chr17:44581757-44592623 (+)
JF1/MsJ ENSUMUG00000034682
 protein coding gene Chr17:46708051-46718996 (+)
LP/J ENSMUSG00230038054
 protein coding gene Chr17:47933326-47944230 (+)
NOD/ShiLtJ ENSMUSG00190016687
 protein coding gene Chr17:44080264-44091128 (+)
NZO/HlLtJ ENSMUSG00225042631
 protein coding gene Chr17:50186023-50196882 (+)
PWK/PhJ ENSLUMG00010031233
 protein coding gene Chr17:43942709-43953791 (+)
SPRET/EiJ ENSMSPG00010029582
 protein coding gene Chr17:44140731-44149297 (+)
WSB/EiJ ENSIUOG00005026465
 protein coding gene Chr17:44982365-44993254 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320148 NCBI Gene Model | MGI Sequence Detail 10271 C57BL/6J ±  kb
    transcript NM_177083 RefSeq | MGI Sequence Detail 2441 C57BL/6  
    polypeptide NP_796057 RefSeq | MGI Sequence Detail 289 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR052314 Immune receptor domain-containing protein
      IPR003599 Immunoglobulin domain subtype
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR013106 Immunoglobulin V-set domain
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:7581883, MGI:8266400
    References
    more
    • Summaries
      All 23
      Phenotypes 6
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory