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Mindy2 Gene Detail
Summary
  • Symbol
    Mindy2
  • Name
    MINDY lysine 48 deubiquitinase 2
  • Synonyms
    B230380D07Rik, Fam63b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443086
    NCBI Gene: 235461
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:70506296-70564456 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 39.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1201 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443086
 protein coding gene Chr9:70506296-70566429 (-)
129S1/SvImJ ENSMUSG00200043091
 protein coding gene Chr9:67607961-67666553 (-)
A/J ENSMUSG00195025842
 protein coding gene Chr9:67384525-67442680 (-)
AKR/J ENSMUSG00220034434
 protein coding gene Chr9:67518274-67576431 (-)
BALB/cJ ENSMUSG00180016342
 protein coding gene Chr9:67498876-67557022 (-)
C3H/HeJ ENSMUSG00175010973
 protein coding gene Chr9:67512242-67570388 (-)
C57BL/6NJ ENSMUSG00215031245
 protein coding gene Chr9:67450141-67508303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032405
 protein coding gene Chr9:67768674-67825899 (-)
CAST/EiJ ENSTCUG00005026286
 protein coding gene Chr9:67326568-67383739 (-)
CBA/J ENSMUSG00210013944
 protein coding gene Chr9:67592956-67651111 (-)
DBA/2J ENSMUSG00185033375
 protein coding gene Chr9:67616678-67674826 (-)
FVB/NJ ENSMUSG00205019442
 protein coding gene Chr9:67890926-67949078 (-)
JF1/MsJ ENSUMUG00000010705
 protein coding gene Chr9:67652577-67709183 (-)
LP/J ENSMUSG00230024800
 protein coding gene Chr9:67803106-67861694 (-)
NOD/ShiLtJ ENSMUSG00190020651
 protein coding gene Chr9:67715381-67773538 (-)
NZO/HlLtJ ENSMUSG00225045657
 protein coding gene Chr9:67922068-67980191 (-)
PWK/PhJ ENSLUMG00010026492
 protein coding gene Chr9:67590049-67646162 (-)
SPRET/EiJ ENSMSPG00010019082
 protein coding gene Chr9:68677380-68728279 (-)
WSB/EiJ ENSIUOG00005023636
 protein coding gene Chr9:67080322-67138938 (-)



Homology
more
  • Human Ortholog
    MINDY2, MINDY lysine 48 deubiquitinase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MINDY2, MINDY lysine 48 deubiquitinase 2
  • Synonyms
    FAM63B
  • Links
    NCBI Gene ID: 54629
    UniProt: Q8NBR6

  • Chr Location
    15q21.3-q22.1; chr15:58771117-58861900 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    14
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042444 Ensembl Gene Model | MGI Sequence Detail 58161 C57BL/6J ±  kb
    transcript ENSMUST00000049031 Ensembl | MGI Sequence Detail 8081 Not Applicable  
    polypeptide ENSMUSP00000037035 Ensembl | MGI Sequence Detail 601 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2143071, MGI:5897445
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory