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Lrp11 Gene Detail
Summary
  • Symbol
    Lrp11
  • Name
    low density lipoprotein receptor-related protein 11
  • Synonyms
    1700034J19Rik, 9830160H19Rik
Location &
Maps
more
  • Sequence Map
    Chr10:7465564-7501247 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 2.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1098 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442989
 protein coding gene Chr10:7465532-7501247 (+)
129S1/SvImJ ENSMUSG00200008892
 protein coding gene Chr10:4460560-4496232 (+)
A/J ENSMUSG00195008350
 protein coding gene Chr10:4349340-4384986 (+)
AKR/J ENSMUSG00220007524
 protein coding gene Chr10:4467654-4503304 (+)
BALB/cJ ENSMUSG00180021789
 protein coding gene Chr10:4511441-4547085 (+)
C3H/HeJ ENSMUSG00175012122
 protein coding gene Chr10:4502811-4538827 (+)
C57BL/6NJ ENSMUSG00215004760
 protein coding gene Chr10:4403755-4439439 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015097
 protein coding gene Chr10:4162867-4197803 (+)
CAST/EiJ ENSTCUG00005017356
 protein coding gene Chr10:4461503-4497464 (+)
CBA/J ENSMUSG00210012457
 protein coding gene Chr10:4448594-4484610 (+)
DBA/2J ENSMUSG00185009181
 protein coding gene Chr10:4494998-4531017 (+)
FVB/NJ ENSMUSG00205008244
 protein coding gene Chr10:4448021-4484039 (+)
JF1/MsJ ENSUMUG00000021849
 protein coding gene Chr10:4581213-4616504 (+)
LP/J ENSMUSG00230013738
 protein coding gene Chr10:6110388-6146037 (+)
NOD/ShiLtJ ENSMUSG00190022229
 protein coding gene Chr10:4440003-4475794 (+)
NZO/HlLtJ ENSMUSG00225015757
 protein coding gene Chr10:10633395-10669043 (+)
PWK/PhJ ENSLUMG00010019301
 protein coding gene Chr10:4315849-4351150 (+)
SPRET/EiJ ENSMSPG00010006408
 protein coding gene Chr10:4677981-4710661 (+)
WSB/EiJ ENSIUOG00005013515
 protein coding gene Chr10:4374850-4410527 (+)



Homology
more
  • Human Ortholog
    LRP11, LDL receptor related protein 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRP11, LDL receptor related protein 11
  • Synonyms
    bA350J20.3, MANSC3
  • Links
    NCBI Gene ID: 84918
    UniProt: Q86VZ4

  • Chr Location
    6q25.1; chr6:149818757-149864424 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    765
  • Tissues
    41
  • cDNA Data
    30
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000019796 Ensembl Gene Model | MGI Sequence Detail 35684 C57BL/6J ±  kb
    transcript ENSMUST00000019931 Ensembl | MGI Sequence Detail 3386 Not Applicable  
    polypeptide ENSMUSP00000019931 Ensembl | MGI Sequence Detail 483 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000009918 low-density lipoprotein receptor-related protein 11
      (term hierarchy)
    • InterPro Domains
      IPR013783 Immunoglobulin-like fold
      IPR036055 LDL receptor-like superfamily
      IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
      IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
      IPR013980 MANSC domain
      IPR035986 PKD domain superfamily
      IPR011106 Seven cysteines, N-terminal
    • GlyGen
      Q8CB67 3 sites, 3 N-linked glycans (3 sites)
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 30
      Antibodies 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1920525
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 7
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory