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Slc25a40 Gene Detail
Summary
  • Symbol
    Slc25a40
  • Name
    solute carrier family 25, member 40
  • Synonyms
    B230315F11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442486
    NCBI Gene: 319653
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:8472850-8504797 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 3.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    744 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442486
 protein coding gene Chr5:8472730-8504840 (+)
129S1/SvImJ ENSMUSG00200001917
 protein coding gene Chr5:5166486-5198494 (+)
A/J ENSMUSG00195007384
 protein coding gene Chr5:5176789-5208800 (+)
AKR/J ENSMUSG00220001886
 protein coding gene Chr5:5088974-5120987 (+)
BALB/cJ ENSMUSG00180016080
 protein coding gene Chr5:4932467-4964478 (+)
C3H/HeJ ENSMUSG00175025379
 protein coding gene Chr5:5107684-5139696 (+)
C57BL/6NJ ENSMUSG00215020626
 protein coding gene Chr5:5389338-5421285 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026957
 protein coding gene Chr5:5032232-5060223 (+)
CAST/EiJ ENSTCUG00005001363
 protein coding gene Chr5:5286988-5318970 (+)
CBA/J ENSMUSG00210002541
 protein coding gene Chr5:5473888-5505904 (+)
DBA/2J ENSMUSG00185027450
 protein coding gene Chr5:5476093-5508103 (+)
FVB/NJ ENSMUSG00205007864
 protein coding gene Chr5:5184500-5216512 (+)
JF1/MsJ ENSUMUG00000002283
 protein coding gene Chr5:5514735-5552904 (+)
LP/J ENSMUSG00230002633
 protein coding gene Chr5:9423958-9455967 (+)
NOD/ShiLtJ ENSMUSG00190012729
 protein coding gene Chr5:4992583-5030677 (+)
NZO/HlLtJ ENSMUSG00225008456
 protein coding gene Chr5:13159337-13191346 (+)
PWK/PhJ ENSLUMG00010018550
 protein coding gene Chr5:5413951-5452265 (+)
SPRET/EiJ ENSMSPG00010004685
 protein coding gene Chr5:5321838-5350230 (+)
WSB/EiJ ENSIUOG00005022726
 protein coding gene Chr5:5189772-5221764 (+)



Homology
more
  • Human Ortholog
    SLC25A40, solute carrier family 25 member 40
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A40, solute carrier family 25 member 40
  • Synonyms
    MCFP
  • Links
    NCBI Gene ID: 55972
    UniProt: Q8TBP6

  • Chr Location
    7q21.12; chr7:87833561-87876404 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a gene-trapped allele are viable and overtly normal in a battery of physiological, metabolic, and behavioral assays.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    42
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054099 Ensembl Gene Model | MGI Sequence Detail 31948 C57BL/6J ±  kb
transcript ENSMUST00000066921 Ensembl | MGI Sequence Detail 2784 Not Applicable  
polypeptide ENSMUSP00000067611 Ensembl | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000030213 mitochondrial glutathione transporter SLC25A40
    (term hierarchy)
  • InterPro Domains
    IPR002067 Mitochondrial carrier protein
    IPR023395 Mitochondrial carrier protein domain superfamily
    IPR045315 Mitochondrial carrier protein Mtm1-like
    IPR018108 Mitochondrial carrier protein, transmembrane region
  • GlyGen
    Q8BGP6 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 43
    cDNA 42
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory