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Rxfp3 Gene Detail
Summary
  • Symbol
    Rxfp3
  • Name
    relaxin family peptide receptor 3
  • Synonyms
    Rln3r1, Salpr
Location &
Maps
more
  • Sequence Map
    Chr15:11033803-11038054 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 5.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    256 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441827
 protein coding gene Chr15:11033803-11038077 (-)
129S1/SvImJ ENSMUSG00200032904
 protein coding gene Chr15:8010114-8014388 (-)
A/J ENSMUSG00195009883
 protein coding gene Chr15:7910807-7915085 (-)
AKR/J ENSMUSG00220022354
 protein coding gene Chr15:7851285-7855559 (-)
BALB/cJ ENSMUSG00180031873
 protein coding gene Chr15:7922216-7926490 (-)
C3H/HeJ ENSMUSG00175028557
 protein coding gene Chr15:8079446-8083720 (-)
C57BL/6NJ ENSMUSG00215024344
 protein coding gene Chr15:7965107-7969381 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019672
 protein coding gene Chr15:7433173-7437429 (-)
CAST/EiJ ENSTCUG00005025266
 protein coding gene Chr15:8043502-8047792 (-)
CBA/J ENSMUSG00210025246
 protein coding gene Chr15:8064467-8068741 (-)
DBA/2J ENSMUSG00185030941
 protein coding gene Chr15:8021530-8025804 (-)
FVB/NJ ENSMUSG00205020177
 protein coding gene Chr15:7897568-7901846 (-)
JF1/MsJ ENSUMUG00000035199
 protein coding gene Chr15:8123044-8127354 (-)
LP/J ENSMUSG00230014882
 protein coding gene Chr15:11503027-11507301 (-)
NOD/ShiLtJ ENSMUSG00190009934
 protein coding gene Chr15:7978507-7982781 (-)
NZO/HlLtJ ENSMUSG00225024042
 protein coding gene Chr15:11742761-11747035 (-)
PWK/PhJ ENSLUMG00010033348
 protein coding gene Chr15:8181340-8185642 (-)
SPRET/EiJ ENSMSPG00010028374
 protein coding gene Chr15:8198265-8200313 (-)
WSB/EiJ ENSIUOG00005029768
 protein coding gene Chr15:7972008-7976300 (-)



Homology
more
  • Human Ortholog
    RXFP3, relaxin family peptide receptor 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RXFP3, relaxin family peptide receptor 3
  • Synonyms
    GPCR135, RLN3R1, RXFPR3, SALPR
  • Links
    NCBI Gene ID: 51289
    UniProt: Q9NSD7

  • Chr Location
    5p13.2; chr5:33936386-33938918 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 3 alleles in 3 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display a subtle decrease in anxiety related behaviors and hypoactivity in their home cages.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    683
  • Tissues
    69
  • cDNA Data
    14
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 239336 NCBI Gene Model | MGI Sequence Detail 4252 C57BL/6J ±  kb
    transcript NM_178717 RefSeq | MGI Sequence Detail 4252 C57BL/6  
    polypeptide Q8BGE9 UniProt | EBI | MGI Sequence Detail 472 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 1
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory