About   Help   FAQ
Gpr141b Gene Detail
Summary
  • Symbol
    Gpr141b
  • Name
    G protein-coupled receptor 141B
  • Synonyms
    A530099J19Rik, Karma
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441809
    NCBI Gene: 319293
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:19911596-19917121 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 7.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441809
 protein coding gene Chr13:19911587-19917125 (-)
129S1/SvImJ ENSMUSG00200012482
 protein coding gene Chr13:17158690-17164205 (-)
A/J ENSMUSG00195033850
 protein coding gene Chr13:16271756-16277275 (-)
AKR/J ENSMUSG00220029751
 protein coding gene Chr13:16178134-16183661 (-)
BALB/cJ ENSMUSG00180031429
 protein coding gene Chr13:16632402-16637921 (-)
C3H/HeJ ENSMUSG00175028837
 protein coding gene Chr13:16707777-16713304 (-)
C57BL/6NJ ENSMUSG00215023022
 protein coding gene Chr13:16668071-16673596 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018256
 protein coding gene Chr13:15070092-15075583 (-)
CAST/EiJ ENSTCUG00005012839
 protein coding gene Chr13:16748397-16753944 (-)
CBA/J ENSMUSG00210030192
 protein coding gene Chr13:16562374-16567901 (-)
DBA/2J ENSMUSG00185012681
 protein coding gene Chr13:17263727-17269254 (-)
FVB/NJ ENSMUSG00205020673
 protein coding gene Chr13:16428090-16433609 (-)
JF1/MsJ ENSUMUG00000012362
 protein coding gene Chr13:16996669-17002171 (-)
LP/J ENSMUSG00230033425
 protein coding gene Chr13:26678938-26684465 (-)
NOD/ShiLtJ ENSMUSG00190018908
 protein coding gene Chr13:16536218-16541745 (-)
NZO/HlLtJ ENSMUSG00225045460
 protein coding gene Chr13:20430997-20436522 (-)
PWK/PhJ ENSLUMG00010027285
 protein coding gene Chr13:15976560-15982066 (-)
SPRET/EiJ ENSMSPG00010016386
 protein coding gene Chr13:15689122-15694636 (-)
WSB/EiJ ENSIUOG00005030800
 protein coding gene Chr13:15901213-15906727 (-)



Homology
more
  • Human Ortholog
    GPR141BP, G protein-coupled receptor 141B, pseudogene
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR141BP, G protein-coupled receptor 141B, pseudogene
  • Links
    NCBI Gene ID: 100420413

  • Chr Location
    chr7:37796058-37796888 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047462 Ensembl Gene Model | MGI Sequence Detail 5526 C57BL/6J ±  kb
transcript ENSMUST00000151029 Ensembl | MGI Sequence Detail 2764 Not Applicable  
polypeptide ENSMUSP00000158601 Ensembl | MGI Sequence Detail 299 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR047160 G-protein coupled receptor 183-like
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
Other
Accession IDs
less
MGI:6159590
References
more
  • Summaries
    All 37
    Gene Ontology 3
    Phenotypes 20
  • Earliest
    J:71411 Arkell RM, et al., Genetic, physical, and phenotypic characterization of the Del(13)Svea36H mouse. Mamm Genome. 2001 Sep;12(9):687-94
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory