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Gipc3 Gene Detail
Summary
  • Symbol
    Gipc3
  • Name
    GIPC PDZ domain containing family, member 3
  • Synonyms
    Ahl5, Gipc3, Rgs19ip3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387006
    NCBI Gene: 209047
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81171099-81179100 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    211 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387006
 protein coding gene Chr10:81171096-81179452 (-)
129S1/SvImJ ENSMUSG00200043081
 protein coding gene Chr10:77798246-77806247 (-)
A/J ENSMUSG00195048859
 protein coding gene Chr10:78193519-78201514 (-)
AKR/J ENSMUSG00220046131
 protein coding gene Chr10:77791204-77799199 (-)
BALB/cJ ENSMUSG00180052396
 protein coding gene Chr10:78203969-78211964 (-)
C3H/HeJ ENSMUSG00175044330
 protein coding gene Chr10:78074722-78082723 (-)
C57BL/6NJ ENSMUSG00215048027
 protein coding gene Chr10:77816582-77824583 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015635
 protein coding gene Chr10:75338183-75344178 (-)
CAST/EiJ ENSTCUG00005050713
 protein coding gene Chr10:77698408-77706412 (-)
CBA/J ENSMUSG00210049811
 protein coding gene Chr10:77930747-77938748 (-)
DBA/2J ENSMUSG00185047464
 protein coding gene Chr10:78273180-78281181 (-)
FVB/NJ ENSMUSG00205034098
 protein coding gene Chr10:77985998-77993999 (-)
JF1/MsJ ENSUMUG00000022415
 protein coding gene Chr10:79500728-79508734 (-)
LP/J ENSMUSG00230050485
 protein coding gene Chr10:80042764-80050765 (-)
NOD/ShiLtJ ENSMUSG00190044289
 protein coding gene Chr10:78186879-78194874 (-)
NZO/HlLtJ ENSMUSG00225052477
 protein coding gene Chr10:84329328-84337329 (-)
PWK/PhJ ENSLUMG00010045103
 protein coding gene Chr10:77864434-77872419 (-)
SPRET/EiJ ENSMSPG00010032122
 protein coding gene Chr10:79474438-79482123 (-)
WSB/EiJ ENSIUOG00005050285
 protein coding gene Chr10:77927113-77935158 (-)



Homology
more
  • Human Ortholog
    GIPC3, GIPC PDZ domain containing family member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GIPC3, GIPC PDZ domain containing family member 3
  • Synonyms
    C19orf64, DFNB15, DFNB72, DFNB95
  • Links
    NCBI Gene ID: 126326
    UniProt: Q8TF64

  • Chr Location
    19p13.3; chr19:3585478-3593541 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human GIPC3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    614
  • Tissues
    16
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034872 Ensembl Gene Model | MGI Sequence Detail 8002 C57BL/6J ±  kb
    transcript ENSMUST00000045102 Ensembl | MGI Sequence Detail 3521 Not Applicable  
    polypeptide ENSMUSP00000049236 Ensembl | MGI Sequence Detail 297 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 2
      Primer pair 1
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3514193
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Phenotypes 19
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory