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Ice1 Gene Detail
Summary
  • Symbol
    Ice1
  • Name
    interactor of little elongation complex ELL subunit 1
  • Synonyms
    BC018507, MGC:27742, mKIAA0947
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385865
    NCBI Gene: 218333
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:70736808-70785958 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 35.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1268 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385865
 protein coding gene Chr13:70699826-70785958 (-)
129S1/SvImJ ENSMUSG00200010239
 protein coding gene Chr13:65099874-65149522 (-)
A/J ENSMUSG00195026172
 protein coding gene Chr13:65733135-65782795 (-)
AKR/J ENSMUSG00220034534
 protein coding gene Chr13:64322041-64371679 (-)
BALB/cJ ENSMUSG00180022391
 protein coding gene Chr13:66231590-66281247 (-)
C3H/HeJ ENSMUSG00175008128
 protein coding gene Chr13:66504968-66554608 (-)
C57BL/6NJ ENSMUSG00215005576
 protein coding gene Chr13:66263718-66313355 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018694
 protein coding gene Chr13:65291307-65340991 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210008289
 protein coding gene Chr13:65827850-65877486 (-)
DBA/2J ENSMUSG00185008648
 protein coding gene Chr13:69524049-69573684 (-)
FVB/NJ ENSMUSG00205019280
 protein coding gene Chr13:65214278-65263920 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230031411
 protein coding gene Chr13:79442255-79491871 (-)
NOD/ShiLtJ ENSMUSG00190035849
 protein coding gene Chr13:65845258-65894895 (-)
NZO/HlLtJ ENSMUSG00225027983
 protein coding gene Chr13:71932546-71982182 (-)
PWK/PhJ ENSLUMG00010010620
 protein coding gene Chr13:65321598-65371923 (-)
SPRET/EiJ ENSMSPG00010030088
 protein coding gene Chr13:66185622-66273705 (-)
WSB/EiJ ENSIUOG00005019237
 protein coding gene Chr13:64742061-64791651 (-)



Homology
more
  • Human Ortholog
    ICE1, interactor of little elongation complex ELL subunit 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ICE1, interactor of little elongation complex ELL subunit 1
  • Synonyms
    KIAA0947
  • Links
    NCBI Gene ID: 23379
    UniProt: Q9Y2F5

  • Chr Location
    5p15.32; chr5:5420664-5490220 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    168
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218333 NCBI Gene Model | MGI Sequence Detail 49151 C57BL/6J ±  kb
transcript NM_144837 RefSeq | MGI Sequence Detail 7675 C57BL/6  
polypeptide E9Q286 UniProt | EBI | MGI Sequence Detail 2241 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000060185 little elongation complex subunit 1
    (term hierarchy)
  • InterPro Domains
    IPR057881 Little elongation complex subunit 1, C-terminal domain
  • GlyGen
    E9Q286 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 168
    cDNA 168

    Microarray probesets 5
Other
Accession IDs
less
MGI:2145488
References
more
  • Summaries
    All 38
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory