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Nomo1 Gene Detail
Summary
  • Symbol
    Nomo1
  • Name
    nodal modulator 1
  • Synonyms
    D7Ertd156e, MGC:37454, MGC:37848, Nomo, PM5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385850
    NCBI Gene: 211548
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45683122-45733636 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2087 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385850
 protein coding gene Chr7:45683120-45733636 (+)
129S1/SvImJ ENSMUSG00200030072
 protein coding gene Chr7:33295976-33348016 (+)
A/J ENSMUSG00195044243
 protein coding gene Chr7:37315630-37366149 (+)
AKR/J ENSMUSG00220008818
 protein coding gene Chr7:31612324-31662837 (+)
BALB/cJ ENSMUSG00180033354
 protein coding gene Chr7:34191031-34241558 (+)
C3H/HeJ ENSMUSG00175027758
 protein coding gene Chr7:34731904-34783952 (+)
C57BL/6NJ ENSMUSG00215041842
 protein coding gene Chr7:33976028-34026541 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029755
 protein coding gene Chr7:47982310-48033756 (+)
CAST/EiJ ENSTCUG00005047353
 protein coding gene Chr7:37706626-37758663 (+)
CBA/J ENSMUSG00210042379
 protein coding gene Chr7:35086970-35137487 (+)
DBA/2J ENSMUSG00185038177
 protein coding gene Chr7:38978686-39030771 (+)
FVB/NJ ENSMUSG00205039859
 protein coding gene Chr7:34631541-34682046 (+)
JF1/MsJ ENSUMUG00000043607
 protein coding gene Chr7:43458531-43510633 (+)
LP/J ENSMUSG00230051337
 protein coding gene Chr7:44405778-44456343 (+)
NOD/ShiLtJ ENSMUSG00190049069
 protein coding gene Chr7:34959239-35009741 (+)
NZO/HlLtJ ENSMUSG00225013739
 protein coding gene Chr7:42604279-42654954 (+)
PWK/PhJ ENSLUMG00010048782
 protein coding gene Chr7:33922917-33975234 (+)
SPRET/EiJ ENSMSPG00010036410
 protein coding gene Chr7:33696460-33749895 (+)
WSB/EiJ ENSIUOG00005022595
 protein coding gene Chr7:35508122-35558771 (+)



Homology
more
  • Human Ortholog
    NOMO1, NODAL modulator 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOMO1, NODAL modulator 1
  • Synonyms
    Nomo, PM5
  • Links
    NCBI Gene ID: 23420
    UniProt: P69849, Q15155

  • Chr Location
    16p13.11; chr16:14833721-14896157 (+)  GRCh38
  • Human Ortholog
    NOMO2, NODAL modulator 2
  • Synonyms
    Nomo, PM5
  • Links
    NCBI Gene ID: 283820
    UniProt: Q5JPE7

  • Chr Location
    16p12.3; chr16:18417325-18562211 (-)  GRCh38
  • Human Ortholog
    NOMO3, NODAL modulator 3
  • Synonyms
    Nomo
  • Links
    NCBI Gene ID: 408050
    UniProt: P69849

  • Chr Location
    16p13.11; chr16:16232506-16300806 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    672
  • Tissues
    36
  • cDNA Data
    149
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030835 Ensembl Gene Model | MGI Sequence Detail 50515 C57BL/6J ±  kb
transcript ENSMUST00000033121 Ensembl | MGI Sequence Detail 4257 Not Applicable  
polypeptide ENSMUSP00000033121 Ensembl | MGI Sequence Detail 1214 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000033366 rodent-type BOS complex subunit NOMO1
    (term hierarchy)
  • InterPro Domains
    IPR013784 Carbohydrate-binding-like fold
    IPR008969 Carboxypeptidase-like, regulatory domain superfamily
    IPR056191 NOMO, C-terminal transthyretin-like domain
    IPR056187 NOMO, eighth prealbumin-like domain
    IPR056190 NOMO, fifth transthyretin-like domain
    IPR055073 NOMO-like, ninth beta-sandwich domain
    IPR055075 NOMO-like, N-terminal beta-sandwich domain
    IPR056319 NOMO, seventh transthyretin-like domain
    IPR056189 NOMO, third transthyretin-like domain
    IPR051417 Serine-Aspartate Repeat-Containing
  • GlyGen
    Q6GQT9 7 sites, 8 N-linked glycans (5 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 152
    cDNA 150
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1098832
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:327863 Perez-Garcia J, et al., Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration. Cancers (Basel). 2022 Aug 20;14(16)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory