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Tm4sf4 Gene Detail
Summary
  • Symbol
    Tm4sf4
  • Name
    transmembrane 4 superfamily member 4
  • Synonyms
    il-TMP, MGC:19127
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385173
    NCBI Gene: 229302
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:57332831-57349098 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 27.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    614 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385173
 protein coding gene Chr3:57332735-57349098 (+)
129S1/SvImJ ENSMUSG00200022252
 protein coding gene Chr3:54203597-54219962 (+)
A/J ENSMUSG00195031154
 protein coding gene Chr3:54110162-54126904 (+)
AKR/J ENSMUSG00220028036
 protein coding gene Chr3:54173420-54189788 (+)
BALB/cJ ENSMUSG00180022632
 protein coding gene Chr3:54201980-54216424 (+)
C3H/HeJ ENSMUSG00175008476
 protein coding gene Chr3:54043414-54057864 (+)
C57BL/6NJ ENSMUSG00215007176
 protein coding gene Chr3:54485519-54501887 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025005
 protein coding gene Chr3:50865377-50881962 (+)
CAST/EiJ ENSTCUG00005002384
 protein coding gene Chr3:53805630-53822154 (+)
CBA/J ENSMUSG00210003269
 protein coding gene Chr3:54159117-54173575 (+)
DBA/2J ENSMUSG00185027049
 protein coding gene Chr3:54321942-54338294 (+)
FVB/NJ ENSMUSG00205003378
 protein coding gene Chr3:53303125-53319519 (+)
JF1/MsJ ENSUMUG00000001375
 protein coding gene Chr3:53725356-53744010 (+)
LP/J ENSMUSG00230003669
 protein coding gene Chr3:56340388-56356748 (+)
NOD/ShiLtJ ENSMUSG00190027469
 protein coding gene Chr3:54518220-54534591 (+)
NZO/HlLtJ ENSMUSG00225015726
 protein coding gene Chr3:58952806-58969167 (+)
PWK/PhJ ENSLUMG00010005266
 protein coding gene Chr3:53834498-53850763 (+)
SPRET/EiJ ENSMSPG00010007320
 protein coding gene Chr3:54691181-54707574 (+)
WSB/EiJ ENSIUOG00005008624
 protein coding gene Chr3:54291407-54307813 (+)



Homology
more
  • Human Ortholog
    TM4SF4, transmembrane 4 L six family member 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM4SF4, transmembrane 4 L six family member 4
  • Synonyms
    il-TMP, ILTMP
  • Links
    NCBI Gene ID: 7104
    UniProt: P48230

  • Chr Location
    3q25.1; chr3:149474697-149503394 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    751
  • Tissues
    49
  • cDNA Data
    23
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 229302 NCBI Gene Model | MGI Sequence Detail 16268 C57BL/6J ±  kb
    transcript NM_145539 RefSeq | MGI Sequence Detail 1417 C57BL/6  
    polypeptide Q91XD3 UniProt | EBI | MGI Sequence Detail 202 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 23
      Primer pair 1
      Other 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 3
      Phenotypes 18
    • Earliest
      J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory