About   Help   FAQ
Etf1 Gene Detail
Summary
  • Symbol
    Etf1
  • Name
    eukaryotic translation termination factor 1
  • Synonyms
    ERF1, MGC:18745, SUP45L1, TB3-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385071
    NCBI Gene: 225363
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:35035838-35065060 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 18.78 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    585 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385071
 protein coding gene Chr18:35035838-35065060 (-)
129S1/SvImJ ENSMUSG00200042575
 protein coding gene Chr18:32033120-32062745 (-)
A/J ENSMUSG00195032504
 protein coding gene Chr18:32195294-32224538 (-)
AKR/J ENSMUSG00220015984
 protein coding gene Chr18:32177240-32206456 (-)
BALB/cJ ENSMUSG00180020501
 protein coding gene Chr18:32644942-32674181 (-)
C3H/HeJ ENSMUSG00175033329
 protein coding gene Chr18:32146378-32175811 (-)
C57BL/6NJ ENSMUSG00215027474
 protein coding gene Chr18:31904351-31933576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022102
 protein coding gene Chr18:32161379-32190395 (-)
CAST/EiJ ENSTCUG00005020670
 protein coding gene Chr18:31799780-31828968 (-)
CBA/J ENSMUSG00210021439
 protein coding gene Chr18:32187117-32216361 (-)
DBA/2J ENSMUSG00185020269
 protein coding gene Chr18:32121685-32150911 (-)
FVB/NJ ENSMUSG00205030482
 protein coding gene Chr18:31839140-31868349 (-)
JF1/MsJ ENSUMUG00000040439
 protein coding gene Chr18:32273318-32302812 (-)
LP/J ENSMUSG00230042128
 protein coding gene Chr18:34229956-34259580 (-)
NOD/ShiLtJ ENSMUSG00190021424
 protein coding gene Chr18:31900153-31929599 (-)
NZO/HlLtJ ENSMUSG00225046151
 protein coding gene Chr18:34135915-34165121 (-)
PWK/PhJ ENSLUMG00010010591
 protein coding gene Chr18:32419351-32448558 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005007577
 protein coding gene Chr18:31900745-31929985 (-)



Homology
more
  • Human Ortholog
    ETF1, eukaryotic translation termination factor 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ETF1, eukaryotic translation termination factor 1
  • Synonyms
    D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1
  • Links
    NCBI Gene ID: 2107
    UniProt: P62495

  • Chr Location
    5q31.2; chr5:138506093-138543239 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    641
  • Tissues
    30
  • cDNA Data
    243
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225363 NCBI Gene Model | MGI Sequence Detail 29223 C57BL/6J ±  kb
transcript NM_144866 RefSeq | MGI Sequence Detail 3718 C57BL/6  
polypeptide Q8BWY3 UniProt | EBI | MGI Sequence Detail 437 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 244
    cDNA 243
    Primer pair 1

    Microarray probesets 12
Other
Accession IDs
less
MGI:2147237
References
more
  • Summaries
    All 49
    Developmental Gene Expression 2
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:49569 Hoshino S, et al., Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1. J Biol Chem. 1998 Aug 28;273(35):22254-9
  • Latest
    J:332882 Li N, et al., CFIm-mediated alternative polyadenylation safeguards the development of mammalian pre-implantation embryos. Stem Cell Reports. 2023 Jan 10;18(1):81-96
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory