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Tmem51 Gene Detail
Summary
  • Symbol
    Tmem51
  • Name
    transmembrane protein 51
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384874
    NCBI Gene: 214359
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:141758303-141811615 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 75.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1860 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384874
 protein coding gene Chr4:141758301-141811985 (-)
129S1/SvImJ ENSMUSG00200043377
 protein coding gene Chr4:135179555-135232520 (-)
A/J ENSMUSG00195029784
 protein coding gene Chr4:136529237-136582744 (-)
AKR/J ENSMUSG00220042861
 protein coding gene Chr4:135531768-135584925 (-)
BALB/cJ ENSMUSG00180043723
 protein coding gene Chr4:134165348-134218845 (-)
C3H/HeJ ENSMUSG00175038924
 protein coding gene Chr4:135193278-135246461 (-)
C57BL/6NJ ENSMUSG00215048217
 protein coding gene Chr4:136711824-136765348 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026758
 protein coding gene Chr4:131714504-131767025 (-)
CAST/EiJ ENSTCUG00005012853
 protein coding gene Chr4:136152627-136205806 (-)
CBA/J ENSMUSG00210025290
 protein coding gene Chr4:134817201-134870370 (-)
DBA/2J ENSMUSG00185050352
 protein coding gene Chr4:136318633-136371514 (-)
FVB/NJ ENSMUSG00205019538
 protein coding gene Chr4:134581094-134634498 (-)
JF1/MsJ ENSUMUG00000034024
 protein coding gene Chr4:137014951-137068067 (-)
LP/J ENSMUSG00230039146
 protein coding gene Chr4:140117190-140170161 (-)
NOD/ShiLtJ ENSMUSG00190022982
 protein coding gene Chr4:134571330-134624201 (-)
NZO/HlLtJ ENSMUSG00225007996
 protein coding gene Chr4:146067223-146120620 (-)
PWK/PhJ ENSLUMG00010039488
 protein coding gene Chr4:134005383-134058254 (-)
SPRET/EiJ ENSMSPG00010031384
 protein coding gene Chr4:136052022-136059289 (-)
WSB/EiJ ENSIUOG00005046232
 protein coding gene Chr4:134469954-134523291 (-)



Homology
more
  • Human Ortholog
    TMEM51, transmembrane protein 51
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM51, transmembrane protein 51
  • Synonyms
    C1orf72
  • Links
    NCBI Gene ID: 55092
    UniProt: Q9NW97

  • Chr Location
    1p36.21; chr1:15152498-15220484 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    648
  • Tissues
    35
  • cDNA Data
    44
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040616 Ensembl Gene Model | MGI Sequence Detail 53313 C57BL/6J ±  kb
    transcript ENSMUST00000036572 Ensembl | MGI Sequence Detail 1875 Not Applicable  
    polypeptide ENSMUSP00000042919 Ensembl | MGI Sequence Detail 249 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 44

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 15
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory