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Tmem161a Gene Detail
Summary
  • Symbol
    Tmem161a
  • Name
    transmembrane protein 161A
  • Synonyms
    MGC:29210
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384577
    NCBI Gene: 234371
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70625006-70636331 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    316 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384577
protein coding gene Chr8:70624979-70636331 (+)
129S1/SvImJ ENSMUSG00200027256
protein coding gene Chr8:65424174-65435800 (+)
A/J ENSMUSG00195013008
protein coding gene Chr8:65754511-65765982 (+)
AKR/J ENSMUSG00220021136
protein coding gene Chr8:65669572-65681212 (+)
BALB/cJ ENSMUSG00180024634
protein coding gene Chr8:65400545-65412172 (+)
C3H/HeJ ENSMUSG00175021225
protein coding gene Chr8:65680512-65692139 (+)
C57BL/6NJ ENSMUSG00215030332
protein coding gene Chr8:65357344-65368812 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031134
protein coding gene Chr8:62380184-62390998 (+)
CAST/EiJ ENSTCUG00005031873
protein coding gene Chr8:65155081-65166568 (+)
CBA/J ENSMUSG00210030592
protein coding gene Chr8:65446070-65457696 (+)
DBA/2J ENSMUSG00185010262
protein coding gene Chr8:71605686-71617311 (+)
FVB/NJ ENSMUSG00205041658
protein coding gene Chr8:64950286-64961910 (+)
JF1/MsJ ENSUMUG00000028514
protein coding gene Chr8:73883279-73894746 (+)
LP/J ENSMUSG00230031329
protein coding gene Chr8:75217242-75228867 (+)
NOD/ShiLtJ ENSMUSG00190020857
protein coding gene Chr8:65363987-65375457 (+)
NZO/HlLtJ ENSMUSG00225046517
protein coding gene Chr8:78626991-78638386 (+)
PWK/PhJ ENSLUMG00010031881
protein coding gene Chr8:65341777-65353213 (+)
SPRET/EiJ ENSMSPG00010034446
protein coding gene Chr8:67031566-67042585 (+)
WSB/EiJ ENSIUOG00005024133
protein coding gene Chr8:66237290-66248710 (+)



Homology
more
  • Human Ortholog
    TMEM161A, transmembrane protein 161A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM161A, transmembrane protein 161A
  • Synonyms
    AROS-29, AROS29
  • Links
    NCBI Gene ID: 54929
    UniProt: Q9NX61

  • Chr Location
    19p13.11; chr19:19119169-19138513 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002342 Ensembl Gene Model | MGI Sequence Detail 11326 C57BL/6J ±  kb
transcript ENSMUST00000002413 Ensembl | MGI Sequence Detail 3018 Not Applicable  
polypeptide ENSMUSP00000002413 Ensembl | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142536, MGI:2142833
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:341688 Xie X, et al., SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory