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Plppr2 Gene Detail
Summary
  • Symbol
    Plppr2
  • Name
    phospholipid phosphatase related 2
  • Synonyms
    BC018242, Lppr2, MGC:25492, PRG-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384575
    NCBI Gene: 235044
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:21848329-21860203 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 7.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    299 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384575
 protein coding gene Chr9:21848306-21860203 (+)
129S1/SvImJ ENSMUSG00200048748
 protein coding gene Chr9:18802574-18814466 (+)
A/J ENSMUSG00195033698
 protein coding gene Chr9:18639213-18651097 (+)
AKR/J ENSMUSG00220031493
 protein coding gene Chr9:18641639-18653522 (+)
BALB/cJ ENSMUSG00180039480
 protein coding gene Chr9:18773503-18785387 (+)
C3H/HeJ ENSMUSG00175036767
 protein coding gene Chr9:18736039-18747924 (+)
C57BL/6NJ ENSMUSG00215036168
 protein coding gene Chr9:18733336-18745217 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031888
 protein coding gene Chr9:17940959-17952752 (+)
CAST/EiJ ENSTCUG00005031089
 protein coding gene Chr9:18779963-18791757 (+)
CBA/J ENSMUSG00210036822
 protein coding gene Chr9:18716972-18728865 (+)
DBA/2J ENSMUSG00185024623
 protein coding gene Chr9:18832272-18844155 (+)
FVB/NJ ENSMUSG00205033737
 protein coding gene Chr9:19068298-19080160 (+)
JF1/MsJ ENSUMUG00000043708
 protein coding gene Chr9:18933578-18945406 (+)
LP/J ENSMUSG00230037956
 protein coding gene Chr9:19227497-19239354 (+)
NOD/ShiLtJ ENSMUSG00190031149
 protein coding gene Chr9:18761271-18773127 (+)
NZO/HlLtJ ENSMUSG00225047910
 protein coding gene Chr9:19174240-19186126 (+)
PWK/PhJ ENSLUMG00010038877
 protein coding gene Chr9:18824741-18836536 (+)
SPRET/EiJ ENSMSPG00010018634
 protein coding gene Chr9:19053881-19064486 (+)
WSB/EiJ ENSIUOG00005044208
 protein coding gene Chr9:18303202-18315073 (+)



Homology
more
  • Human Ortholog
    PLPPR2, phospholipid phosphatase related 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPPR2, phospholipid phosphatase related 2
  • Synonyms
    LPPR2, PRG4
  • Links
    NCBI Gene ID: 64748
    UniProt: Q96GM1

  • Chr Location
    19p13.2; chr19:11355386-11365698 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    894
  • Tissues
    36
  • cDNA Data
    29
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040563 Ensembl Gene Model | MGI Sequence Detail 11875 C57BL/6J ±  kb
transcript ENSMUST00000046371 Ensembl | MGI Sequence Detail 2626 Not Applicable  
polypeptide ENSMUSP00000038616 Ensembl | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000009904 phospholipid phosphatase-related protein type 2
    (term hierarchy)
  • InterPro Domains
    IPR043216 Phosphatidic acid phosphatases-like
    IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
    IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
  • GlyGen
    Q8VCY8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 31
    cDNA 30
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:89819 Savaskan NE, et al., Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family. Eur J Neurosci. 2004 Jan;19(1):212-20
  • Latest
    J:323226 Gross I, et al., Systematic expression analysis of plasticity-related genes in mouse brain development brings PRG4 into play. Dev Dyn. 2022 Apr;251(4):714-728
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory