About   Help   FAQ
Oxr1 Gene Detail
Summary
  • Symbol
    Oxr1
  • Name
    oxidation resistance 1
  • Synonyms
    2210416C20Rik, C7, C7B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179326
    NCBI Gene: 170719
  • Alliance
  • Transcription Start Sites
    32 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:41310878-41724444 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 16.06 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13464 from dbSNP Build 142
  • Strain Annotations
    30
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2179326
protein coding gene Chr15:41310745-41724447 (+)
129S1/SvImJ ENSMUSGG00200054757
protein coding gene Chr15:38537522-38653975 (+)
129S1/SvImJ ENSMUSG00200025020
protein coding gene Chr15:38657874-38687180 (+)
A/J ENSMUSG00195033345
protein coding gene Chr15:38639882-38669206 (+)
A/J ENSMUSGG00195055262
protein coding gene Chr15:38519192-38635979 (+)
AKR/J ENSMUSG00220025927
protein coding gene Chr15:38534355-38563652 (+)
AKR/J ENSMUSGG00220054780
protein coding gene Chr15:38413872-38530456 (+)
BALB/cJ ENSMUSGG00180055502
protein coding gene Chr15:38493018-38609945 (+)
BALB/cJ ENSMUSG00180030410
protein coding gene Chr15:38613848-38642224 (+)
C3H/HeJ ENSMUSGG00175054933
protein coding gene Chr15:38668382-38784968 (+)
C3H/HeJ ENSMUSG00175025231
protein coding gene Chr15:38788867-38818168 (+)
C57BL/6NJ ENSMUSG00215015396
protein coding gene Chr15:38608368-38636745 (+)
C57BL/6NJ ENSMUSGG00215055656
protein coding gene Chr15:38487530-38604465 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019764
protein coding gene Chr15:36106807-36514673 (+)
CAST/EiJ ENSTCUGG00005054445
protein coding gene Chr15:38496435-38612787 (+)
CBA/J ENSMUSGG00210055065
protein coding gene Chr15:38612677-38729466 (+)
CBA/J ENSMUSG00210017945
protein coding gene Chr15:38733368-38762691 (+)
DBA/2J ENSMUSG00185033201
protein coding gene Chr15:38714239-38743561 (+)
DBA/2J ENSMUSGG00185057331
protein coding gene Chr15:38593561-38710337 (+)
FVB/NJ ENSMUSGG00205054096
protein coding gene Chr15:38476845-38593625 (+)
FVB/NJ ENSMUSG00205025194
protein coding gene Chr15:38597527-38626849 (+)
JF1/MsJ ENSUMUGG00000058592
protein coding gene Chr15:38436481-38560400 (+)
LP/J ENSMUSG00230011255
protein coding gene Chr15:42040444-42069748 (+)
LP/J ENSMUSGG00230055310
protein coding gene Chr15:41920096-42036545 (+)
NOD/ShiLtJ ENSMUSGG00190054754
protein coding gene Chr15:38547346-38664112 (+)
NOD/ShiLtJ ENSMUSG00190028644
protein coding gene Chr15:38668014-38697342 (+)
NZO/HlLtJ ENSMUSG00225037522
protein coding gene Chr15:42392459-42421781 (+)
NZO/HlLtJ ENSMUSGG00225055505
protein coding gene Chr15:42271791-42388557 (+)
PWK/PhJ ENSLUMGG00010054171
protein coding gene Chr15:38612302-38730436 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOGG00005053867
protein coding gene Chr15:38576197-38692580 (+)



Homology
more
  • Human Ortholog
    OXR1, oxidation resistance 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OXR1, oxidation resistance 1
  • Synonyms
    CHEGDD, Nbla00307, TLDC3
  • Links
    NCBI Gene ID: 55074
    UniProt: Q8N573

  • Chr Location
    8q23.1; chr8:106270144-106752694 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human OXR1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 3 genetic backgrounds
    6 phenotypes from multigenic genotypes
    1 images
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in progressive cerebellar neurodegeneration and ataxia, increased apoptosis in the cerebellar granule cell layer, and premature death.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022307 Ensembl Gene Model | MGI Sequence Detail 413567 C57BL/6J ±  kb
    transcript ENSMUST00000110297 Ensembl | MGI Sequence Detail 4599 Not Applicable  
    polypeptide ENSMUSP00000105926 Ensembl | MGI Sequence Detail 866 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 12
      Primer pair 2
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1922080
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 6
      Gene Ontology 9
      Phenotypes 25
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.
    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory