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Vasn Gene Detail
Summary
  • Symbol
    Vasn
  • Name
    vasorin
  • Synonyms
    2610528G05Rik, ATIA, Slitl2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2177651
    NCBI Gene: 246154
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:4457805-4468666 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 2.46 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    243 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2177651
 protein coding gene Chr16:4457805-4469030 (+)
129S1/SvImJ ENSMUSG00200010553
 protein coding gene Chr16:1449680-1460541 (+)
A/J ENSMUSG00195010758
 protein coding gene Chr16:995416-1006259 (+)
AKR/J ENSMUSG00220016748
 protein coding gene Chr16:1301073-1311935 (+)
BALB/cJ ENSMUSG00180008105
 protein coding gene Chr16:1250616-1261480 (+)
C3H/HeJ ENSMUSG00175028449
 protein coding gene Chr16:1441909-1452770 (+)
C57BL/6NJ ENSMUSG00215009995
 protein coding gene Chr16:1123161-1134025 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020405
 protein coding gene Chr16:908385-919175 (+)
CAST/EiJ ENSTCUG00005027848
 protein coding gene Chr16:1328101-1338959 (+)
CBA/J ENSMUSG00210011812
 protein coding gene Chr16:1459237-1470100 (+)
DBA/2J ENSMUSG00185009556
 protein coding gene Chr16:1404396-1415256 (+)
FVB/NJ ENSMUSG00205010710
 protein coding gene Chr16:1325973-1336841 (+)
JF1/MsJ ENSUMUG00000036406
 protein coding gene Chr16:1435857-1446672 (+)
LP/J ENSMUSG00230011554
 protein coding gene Chr16:3945431-3956292 (+)
NOD/ShiLtJ ENSMUSG00190020807
 protein coding gene Chr16:1479810-1490674 (+)
NZO/HlLtJ ENSMUSG00225022930
 protein coding gene Chr16:7187759-7198620 (+)
PWK/PhJ ENSLUMG00010016298
 protein coding gene Chr16:1303157-1313979 (+)
SPRET/EiJ ENSMSPG00010016174
 protein coding gene Chr16:1254522-1265798 (+)
WSB/EiJ ENSIUOG00005016132
 protein coding gene Chr16:1437537-1448430 (+)



Homology
more
  • Human Ortholog
    VASN, vasorin
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VASN, vasorin
  • Synonyms
    SLITL2
  • Links
    NCBI Gene ID: 114990
    UniProt: Q6EMK4

  • Chr Location
    16p13.3; chr16:4371848-4383538 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted allele exhibit increased sensitivity to TNFalpha-induced lethality, TNFalpha-, cycloheximide-, or CoCl2-induced cell death, and reduced male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    106
  • cDNA Data
    69
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039646 Ensembl Gene Model | MGI Sequence Detail 10862 C57BL/6J ±  kb
    transcript ENSMUST00000038770 Ensembl | MGI Sequence Detail 2829 Not Applicable  
    polypeptide ENSMUSP00000045162 Ensembl | MGI Sequence Detail 673 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 71
      cDNA 70
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1921457
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 6
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:374882 Eijken M, et al., Vasorin-deficient mice display disturbed vitamin D and mineral homeostasis in combination with a low bone mass phenotype. Bone Rep. 2024 Sep;22:101792
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory