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Bspry Gene Detail
Summary
  • Symbol
    Bspry
  • Name
    B-box and SPRY domain containing
  • Synonyms
    zetin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2177191
    NCBI Gene: 192120
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:62398290-62415535 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 33.16 cM, cytoband C1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2177191
 protein coding gene Chr4:62398248-62415537 (+)
129S1/SvImJ ENSMUSG00200002418
 protein coding gene Chr4:57385460-57402701 (+)
A/J ENSMUSG00195008179
 protein coding gene Chr4:57972901-57990136 (+)
AKR/J ENSMUSG00220005506
 protein coding gene Chr4:57777273-57794508 (+)
BALB/cJ ENSMUSG00180028453
 protein coding gene Chr4:56925915-56943152 (+)
C3H/HeJ ENSMUSG00175021157
 protein coding gene Chr4:57723218-57740453 (+)
C57BL/6NJ ENSMUSG00215023597
 protein coding gene Chr4:57793337-57810587 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026081
 protein coding gene Chr4:56526148-56544913 (+)
CAST/EiJ ENSTCUG00005007839
 protein coding gene Chr4:57540940-57558301 (+)
CBA/J ENSMUSG00210005090
 protein coding gene Chr4:57459412-57476647 (+)
DBA/2J ENSMUSG00185016601
 protein coding gene Chr4:57847126-57864365 (+)
FVB/NJ ENSMUSG00205017579
 protein coding gene Chr4:56174921-56192166 (+)
JF1/MsJ ENSUMUG00000016043
 protein coding gene Chr4:58530608-58548318 (+)
LP/J ENSMUSG00230010999
 protein coding gene Chr4:61366481-61383722 (+)
NOD/ShiLtJ ENSMUSG00190030884
 protein coding gene Chr4:56879475-56898742 (+)
NZO/HlLtJ ENSMUSG00225012640
 protein coding gene Chr4:66394756-66411997 (+)
PWK/PhJ ENSLUMG00010007045
 protein coding gene Chr4:56149207-56166525 (+)
SPRET/EiJ ENSMSPG00010027971
 protein coding gene Chr4:57417552-57437269 (+)
WSB/EiJ ENSIUOG00005019609
 protein coding gene Chr4:57204565-57221800 (+)



Homology
more
  • Human Ortholog
    BSPRY, B-box and SPRY domain containing
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BSPRY, B-box and SPRY domain containing
  • Links
    NCBI Gene ID: 54836
    UniProt: Q5W0U4

  • Chr Location
    9q32; chr9:113349520-113371233 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    68
  • cDNA Data
    70
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028392 Ensembl Gene Model | MGI Sequence Detail 17246 C57BL/6J ±  kb
transcript ENSMUST00000030088 Ensembl | MGI Sequence Detail 1757 Not Applicable  
polypeptide ENSMUSP00000030088 Ensembl | MGI Sequence Detail 486 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 6
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:75634 Schenker T, et al., BSPRY, a novel protein of the Ro-Ret family. Biochim Biophys Acta. 2000 Sep 7;1493(1-2):255-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory