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Mrps2 Gene Detail
Summary
  • Symbol
    Mrps2
  • Name
    mitochondrial ribosomal protein S2
  • Synonyms
    1500019M10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153089
    NCBI Gene: 118451
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:28358078-28361190 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 19.38 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    170 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153089
 protein coding gene Chr2:28355963-28361190 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025522
 protein coding gene Chr2:26527665-26530779 (+)
A/J MGP_AJ_G0025499
 protein coding gene Chr2:25526847-25529959 (+)
AKR/J MGP_AKRJ_G0025469
 protein coding gene Chr2:26367594-26370706 (+)
BALB/cJ MGP_BALBcJ_G0025495
 protein coding gene Chr2:25646384-25649496 (+)
C3H/HeJ MGP_C3HHeJ_G0025256
 protein coding gene Chr2:26289880-26292992 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025939
 protein coding gene Chr2:27428230-27431342 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023350
 protein coding gene Chr2:24330717-24333833 (+)
CAST/EiJ MGP_CASTEiJ_G0024719
 protein coding gene Chr2:26192786-26195899 (+)
CBA/J MGP_CBAJ_G0025234
 protein coding gene Chr2:28357153-28360265 (+)
DBA/2J MGP_DBA2J_G0025367
 protein coding gene Chr2:25332580-25335692 (+)
FVB/NJ MGP_FVBNJ_G0025329
 protein coding gene Chr2:25113775-25116887 (+)
LP/J MGP_LPJ_G0025453
 protein coding gene Chr2:26478391-26481505 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025360
 protein coding gene Chr2:28360918-28364030 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025998
 protein coding gene Chr2:26285474-26288586 (+)
PWK/PhJ MGP_PWKPhJ_G0024467
 protein coding gene Chr2:25139334-25142449 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024267
 protein coding gene Chr2:26417429-26420554 (+)
WSB/EiJ MGP_WSBEiJ_G0024788
 protein coding gene Chr2:26416409-26419522 (+)



Homology
more
  • Human Ortholog
    MRPS2, mitochondrial ribosomal protein S2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPS2, mitochondrial ribosomal protein S2
  • Synonyms
    CGI-91, COXPD36, MRP-S2, S2mt, uS2m
  • Links
    NCBI Gene ID: 51116
    UniProt: Q9Y399

  • Chr Location
    9q34.3; chr9:135499965-135504673 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MRPS2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    16
  • cDNA Data
    68
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035772 Ensembl Gene Model | MGI Sequence Detail 3113 C57BL/6J ±  kb
    transcript ENSMUST00000038600 Ensembl | MGI Sequence Detail 2080 Not Applicable  
    polypeptide ENSMUSP00000036725 Ensembl | MGI Sequence Detail 291 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000010628 small ribosomal subunit protein uS2m
      (term hierarchy)
    • PDB
      7PNT, 7PNU, 7PNV, 7PNW
    • InterPro Domains
      IPR001865 Small ribosomal subunit protein uS2
      IPR005706 Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid
      IPR018130 Small ribosomal subunit protein uS2, conserved site
      IPR023591 Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily
    • GlyGen
      Q924T2 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 70
      cDNA 69
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1923595
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 13
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    01/28/2026
    MGI 6.24     		The Jackson Laboratory