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Gpr137 Gene Detail
Summary
  • Symbol
    Gpr137
  • Name
    G protein-coupled receptor 137
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147529
    NCBI Gene: 107173
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:6915425-6919818 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147529
 protein coding gene Chr19:6915425-6919848 (-)
129S1/SvImJ ENSMUSG00200051044
 protein coding gene Chr19:3640933-3645356 (-)
A/J ENSMUSG00195049789
 protein coding gene Chr19:4042847-4047270 (-)
AKR/J ENSMUSG00220033811
 protein coding gene Chr19:3812280-3816703 (-)
BALB/cJ ENSMUSG00180045041
 protein coding gene Chr19:4406418-4410841 (-)
C3H/HeJ ENSMUSG00175011587
 protein coding gene Chr19:3662860-3667283 (-)
C57BL/6NJ ENSMUSG00215041796
 protein coding gene Chr19:3881364-3885787 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022619
 protein coding gene Chr19:3608116-3612508 (-)
CAST/EiJ ENSTCUG00005030250
 protein coding gene Chr19:3784357-3788785 (-)
CBA/J ENSMUSG00210049511
 protein coding gene Chr19:3666255-3670669 (-)
DBA/2J ENSMUSG00185047177
 protein coding gene Chr19:4042730-4047144 (-)
FVB/NJ ENSMUSG00205034818
 protein coding gene Chr19:4041801-4046209 (-)
JF1/MsJ ENSUMUG00000033524
 protein coding gene Chr19:4002580-4007001 (-)
LP/J ENSMUSG00230053610
 protein coding gene Chr19:4967669-4972092 (-)
NOD/ShiLtJ ENSMUSG00190046198
 protein coding gene Chr19:3574133-3578556 (-)
NZO/HlLtJ ENSMUSG00225026636
 protein coding gene Chr19:8676484-8680907 (-)
PWK/PhJ ENSLUMG00010007035
 protein coding gene Chr19:3767270-3771691 (-)
SPRET/EiJ ENSMSPG00010050011
 protein coding gene Chr19:3759538-3763976 (-)
WSB/EiJ ENSIUOG00005041002
 protein coding gene Chr19:3680431-3684854 (-)



Homology
more
  • Human Ortholog
    GPR137, G protein-coupled receptor 137
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR137, G protein-coupled receptor 137
  • Synonyms
    C11orf4, GPR137A, TM7SF1L1
  • Links
    NCBI Gene ID: 56834
    UniProt: Q96N19

  • Chr Location
    11q13.1; chr11:64270062-64289500 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    643
  • Tissues
    11
  • cDNA Data
    38
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 107173 NCBI Gene Model | MGI Sequence Detail 4394 C57BL/6J ±  kb
transcript NR_189038 RefSeq | MGI Sequence Detail 2206 C57BL/6  
polypeptide Q80ZU9 UniProt | EBI | MGI Sequence Detail 396 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 38
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:83410 Vassilatis DK, et al., The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4903-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory