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Rmdn2 Gene Detail
Summary
  • Symbol
    Rmdn2
  • Name
    regulator of microtubule dynamics 2
  • Synonyms
    Fam82a1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147043
    NCBI Gene: 381110
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:79919292-80000621 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 50.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2175 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147043
 protein coding gene Chr17:79886025-80000630 (+)
129S1/SvImJ ENSMUSGG00200054488
 protein coding gene Chr17:75295806-75360661 (+)
129S1/SvImJ ENSMUSG00200024203
 protein coding gene Chr17:75295806-75296186 (+)
A/J ENSMUSGG00195055360
 protein coding gene Chr17:76659391-76724273 (+)
A/J ENSMUSG00195026149
 protein coding gene Chr17:76659391-76659771 (+)
AKR/J ENSMUSGG00220054836
 protein coding gene Chr17:75567074-75630428 (+)
AKR/J ENSMUSG00220013040
 protein coding gene Chr17:75567074-75567454 (+)
BALB/cJ ENSMUSG00180004529
 protein coding gene Chr17:76369076-76369456 (+)
BALB/cJ ENSMUSGG00180055324
 protein coding gene Chr17:76369076-76433938 (+)
C3H/HeJ ENSMUSG00175015124
 protein coding gene Chr17:75638213-75638593 (+)
C3H/HeJ ENSMUSGG00175054554
 protein coding gene Chr17:75638213-75704949 (+)
C57BL/6NJ ENSMUSGG00215055546
 protein coding gene Chr17:75355873-75420731 (+)
C57BL/6NJ ENSMUSG00215014550
 protein coding gene Chr17:75355873-75356253 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021896
 protein coding gene Chr17:75343766-75401484 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054883
 protein coding gene Chr17:75501542-75566417 (+)
CBA/J ENSMUSG00210020413
 protein coding gene Chr17:75501542-75501922 (+)
DBA/2J ENSMUSG00185012825
 protein coding gene Chr17:78335066-78335446 (+)
DBA/2J ENSMUSGG00185057583
 protein coding gene Chr17:78335066-78399927 (+)
FVB/NJ ENSMUSGG00205054386
 protein coding gene Chr17:76111613-76181984 (+)
FVB/NJ ENSMUSG00205028539
 protein coding gene Chr17:76111613-76111993 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230019731
 protein coding gene Chr17:79336667-79337047 (+)
LP/J ENSMUSGG00230055692
 protein coding gene Chr17:79336667-79401518 (+)
NOD/ShiLtJ ENSMUSGG00190054865
 protein coding gene Chr17:75400287-75465148 (+)
NOD/ShiLtJ ENSMUSG00190009138
 protein coding gene Chr17:75400287-75400667 (+)
NZO/HlLtJ ENSMUSG00225030669
 protein coding gene Chr17:81597632-81598012 (+)
NZO/HlLtJ ENSMUSGG00225055381
 protein coding gene Chr17:81597632-81662484 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RMDN2, regulator of microtubule dynamics 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RMDN2, regulator of microtubule dynamics 2
  • Synonyms
    BLOCK18, FAM82A, FAM82A1, PRO34163, PYST9371, RMD-2, RMD2, RMD4
  • Links
    NCBI Gene ID: 151393
    UniProt: Q96LZ7

  • Chr Location
    2p22.2; chr2:37920901-38067142 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    641
  • Tissues
    5
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036368 Ensembl Gene Model | MGI Sequence Detail 81330 C57BL/6J ±  kb
transcript ENSMUST00000040368 Ensembl | MGI Sequence Detail 1802 Not Applicable  
polypeptide ENSMUSP00000044543 Ensembl | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000030940 regulator of microtubule dynamics protein 2
    (term hierarchy)
  • InterPro Domains
    IPR049039 Regulator of microtubule dynamics protein 1-3, alpha-helical domain
    IPR011990 Tetratricopeptide-like helical domain superfamily
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 5
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:237827 Gineste C, et al., In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Neuromuscul Disord. 2013 Apr;23(4):357-69
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory